102 results
- Videos
Some activities of the Bermondsey Borough Council.
Date: [1931]- Archives and manuscripts
- Online
Livre des simples médecines, in French
Date: c. 1470Reference: MS.626- Digital Images
- Online
Veratrum nigrum L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and, when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying-in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum - and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley- Digital Images
- Online
Carthamus tinctorius L. Asteraceae. Safe Flower, False Saffron - Distribution: W. Asia. Dioscorides (in Beck, 2003) notes the seeds as a purgative, but also advises it made up with 30 figs, which must have helped. Gerard (1640) calls it Atractylis flore luteo the yellow distaffe thistle. and follows Dioscorides in its uses, but does get the reader confused with Cnicus benedictus, calling both plants 'wild bastard saffron'. Culpeper makes no mention of it in his early works, but later (1826) have the following: ‘Wild Saffon, or Saf-flower ... accounted a pretty strong cathartic [causing diarrhoea and vomiting], evacuating tough viscid phlegm, both upwards and downwards, and by that means is said to clear the lungs, and help the phthisic [now equated with tuberculosis]. It is likewise serviceable against the jaundice
Dr Henry Oakeley- Digital Images
- Online
Veratrum album L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum -and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley- Videos
- Online
The story of the Wellcome Foundation Ltd.
Date: 1955- Archives and manuscripts
Heatley, Norman George, OBE (1911- 2004)
Heatley, Norman George, 1911-2004Date: 1902-2004Reference: PP/NHE- Pictures
- Online
A pharmaceutical business (John Bell & Co.): rooms for manufacture, dispensing, and shop. Etching by R.W. Macbeth.
Macbeth, Robert W. (Robert Walker), 1848-1910.Date: [between 1890 and 1899?]Reference: 585841i- Videos
Poisoned. Part 3, The killing fields.
Date: 2000- Pictures
The zodiac man. Watercolour painting by a Persian artist.
Date: [between 1800 and 1899?]Reference: 582971iPart of: Alexandrian series.- Audio
Expert instinct : do animals have medical secrets?.
Date: 2000- Archives and manuscripts
Herbarius, Latinus
Date: c. 1490Reference: MS.346- Archives and manuscripts
Wellcome Foundation Ltd
Wellcome Foundation LtdDate: c.1860-c.1995Reference: WF- Archives and manuscripts
English Language Autograph Letters: HEA-HEY
Date: 1765-1910Reference: MS.8854- Archives and manuscripts
Monthly Memoranda (points for propaganda)
Date: 1930-1931Reference: WF/M/GB/30/06Part of: Wellcome Foundation Ltd- Archives and manuscripts
English Language Autograph Letters: M
Date: 1820-1951Reference: MS.8878- Archives and manuscripts
English Language Autograph Letters: Lagrange-de Lazen
Date: 1800-1965Reference: MS.8890- Archives and manuscripts
English Language Autograph Letters: HIG-HOL
Date: 1820-1905Reference: MS.8930- Archives and manuscripts
Published papers and bibliography
Date: 1979Reference: PP/EBC/G.1Part of: Chain, Professor Sir Ernst Boris- Archives and manuscripts
Hanford
Date: 1976-1997Reference: PP/AMS/P.15Part of: Alice Stewart (1906-2002)- Archives and manuscripts
Fennings Pharmaceuticals
Fennings PharmaceuticalsDate: 1830s-1990sReference: SA/FEN- Archives and manuscripts
The Papers of Rosalind Franklin
Franklin, Rosalind Elsie, 1920-1958, crystallographerDate: 1937-2008Reference: FRKN- Archives and manuscripts
Dent, Charles Enrique (1911-1976)
Dent, Charles Enrique (1911-1976)Date: c.1940-1977Reference: PP/CED- Archives and manuscripts
- Online
Henry Wellcome Letter Book 1 ['HSW Private No.1']
Date: Aug 1882-Mar 1888Reference: WF/E/01/01/01Part of: Wellcome Foundation Ltd- Videos
Ebola the search for a cure.
Date: 2014