128 results
- Digital Images
- Online
The pain of it all, emotional cancer journey, artwork
Michele Angelo Petrone- Videos
- Online
Epidemiology of cancer.
Date: 1974- Videos
Krebs.
Date: 1930- Archives and manuscripts
Hazel Thornton Articles
Hazel ThorntonDate: 2000-2005Reference: PP/HTH/C/1/31/2Part of: Hazel Thornton: Archive- Archives and manuscripts
Cancer Care
Date: 1977-1985Reference: SA/PAT/D/6Part of: The Patients Association- Archives and manuscripts
- Online
Offprints: Neutron Therapy: Breast, Gliobastoma, Rectum, Melanoma, Mesothelioma, Stomach
Date: 1975-1987Reference: PP/CAT/C.6Part of: Dr Mary Catterall- Videos
The gene genie.
Date: 1993- Books
- Online
Enjoy your later life : physical and emotional well being for older women.
Great Britain. Department of HealthDate: 1998- Digital Images
- Online
Taxus baccata L. Taxaceae European Yew. Trees are feminine in Latin, so while Taxus has a masculine ending (-us), its specific name, baccata (meaning 'having fleshy berries' (Stearn, 1994)), agrees with it in gender by having a female ending ( -a). Distribution: Europe. Although regarded as poisonous since Theophrastus, Gerard and his school friends used to eat the red berries (they are technically called 'arils') without harm. Johnson clearly ate the fleshy arils and spat out the seed, which is as poisonous as the leaves. It is a source of taxol, an important chemotherapeutic agent for breast and other cancers. It was first extracted from the bark of T. brevifolia, the Pacific yew tree, in 1966. About 1,100 kg of bark produces 10 g of taxol, and 360,000 trees a year would have been required for the needs of the USA – an unsustainable amount. In 1990 a precursor of taxol was extracted from the needles of the European yew so saving the Pacific trees. It is now produced in fermentation tanks from cell cultures of Taxus. Curiously, there is a fungus, Nodulisporium sylviforme, which lives on the yew tree, that also produces taxol. Because taxol stops cell division, it is also used in the stents that are inserted to keep coronary arteries open. Here it inhibits – in a different way, but like anti-fouling paint on the bottom of ships – the overgrowth of endothelial cells that would otherwise eventually block the tube. The economic costs of anticancer drugs are significant. Paclitaxel ‘Taxol’ for breast cancer costs (2012) £246 every 3 weeks
Dr Henry Oakeley- Videos
- Online
Ultrasound in tumour diagnosis.
Date: 1976- Audio
The royal marsden.
Date: 2006- Books
Why you don't need dairy / by Juliet Gellatley.
Gellatley, JulietDate: [2021?]- Videos
Gene raiders.
Date: 1997- Archives and manuscripts
K: Medical conditions and diseases
Date: 1978-2006Reference: SA/WHL/14Part of: Women's Health Library: archive- Archives and manuscripts
Hazel Thornton: Archive
Hazel ThorntonDate: 1990-2015Reference: PP/HTH- Archives and manuscripts
- Online
Triston, Julia
Date: 9/09/2009Reference: TP1/A/1567Part of: One and Other Project- Archives and manuscripts
- Online
Mary Anning (1799-1847)
Anning, Mary, 1799-1847.Date: 1823Reference: MS.8592- Digital Images
- Online
Sanguinaria canadensis (Bloodroot, Pucoon or Indian paint)
Dr Henry Oakeley- Digital Images
- Online
Sanguinaria canadensis (Bloodroot, Pucoon or Indian paint)
Dr Henry Oakeley- Digital Images
- Online
Sanguinaria canadensis (Bloodroot, Pucoon or Indian paint)
Dr Henry Oakeley- Digital Images
- Online
Atropa belladonna L. Solanaceae. Deadly nightshade. Dwale. Morella, Solatrum, Hound's berries, Uva lupina, Cucubalus, Solanum lethale. Atropa derives from Atropos the oldest of the three Fates of Greek mythology who cut the thread of Life (her sisters Clotho and Lachesis spun and measured the thread, respectively). belladonna, literally, means 'beautiful lady' and was the Italian name for it. Folklore has it that Italian ladies put drops from the plant or the fruits in their eyes to make themselves doe-eyed, myopic and beautiful. However, this is not supported by the 16th and 17th century literature, where no mention is ever made of dilated pupils (or any of the effects of parasympathetic blockade). Tournefort (1719) says 'The Italians named this plant Belladonna, which in their language signifies a beautiful woman, because the ladies use it much in the composition of their Fucus [rouge or deceit or cosmetic] or face paint.' Parkinson says that the Italian ladies use the distilled juice as a fucus '... peradventure [perhaps] to take away their high colour and make them looke paler.' I think it more likely that they absorbed atropine through their skin and were slightly 'stoned' and disinhibited, which made them beautiful ladies in the eyes of Italian males. Distribution: Europe, North Africa, western Asia. Culpeper (1650) writes: 'Solanum. Nightshade: very cold and dry, binding … dangerous given inwardly … outwardly it helps the shingles, St Antonie's Fire [erysipelas] and other hot inflammation.' Most of the 16th, 17th and 18th century herbals recommend it topically for breast cancers. Poisonous plants were regarded as 'cold' plants as an excess of them caused death and the body became cold. They were regarded as opposing the hot humour which kept us warm and alive. Poultices of Belladonna leaves are still recommended for muscle strain in cyclists, by herbalists. Gerard (1633) writes that it: 'causeth sleep, troubleth the mind, bringeth madnesse if a few of the berries be inwardly taken, but if more be taken they also kill...'. He was also aware that the alkaloids could be absorbed through the skin for he notes that a poultice of the leaves applied to the forehead, induces sleep, and relieves headache. The whole plant contains the anticholinergic alkaloid atropine, which blocks the peripheral actions of acetylcholine in the parasympathetic nervous system. Atropine is a racemic mixture of d- and l- hyoscyamine. Atropine, dropped into the eyes, blocks the acetylcholine receptors of the pupil so it no longer constricts on exposure to bright light - so enabling an ophthalmologist to examine the retina with an ophthalmoscope. Atropine speeds up the heart rate, reduces salivation and sweating, reduces gut motility, inhibits the vertigo of sea sickness, and is used to block the acetylcholine receptors to prevent the effects of organophosphorous and other nerve gas poisons. It is still has important uses in medicine. Atropine poisoning takes three or for days to wear off, and the hallucinations experienced by its use are described as unpleasant. We have to be content with 'madness', 'frenzie' and 'idle and vain imaginations' in the early herbals to describe the hallucinations of atropine and related alkaloids as the word 'hallucination' in the sense of a perception for which there is no external stimulus, was not used in English until 1646 (Sir T. Browne, 1646). It is a restricted herbal medicine which can only be sold in premises which are registered pharmacies and by or under the supervision of a pharmacist (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley- Archives and manuscripts
Godfrey-Faussett Family Receipts
Date: 17th century to early 19th centuryReference: MS.8680Part of: Godfrey-Faussett Family Receipts- Archives and manuscripts
Statistics
Date: 1985-1993Reference: SA/ASH/T/5/39Part of: Action on Smoking and Health (ASH)- Archives and manuscripts
Doll, Sir Richard (1912-2005)
Doll, Richard, Sir, 1912-2005Date: 1943-1998Reference: PP/DOL- Books
Genetic effects on environmental vulnerability to disease / edited by Michael Rutter.
Date: 2008