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Aralia spinosa L. Araliaceae. Devil's walking stick, Prickly ash, Hercules' club. Tree. Distribution: Eastern North America. Contact with sap causes skin irritation, raw berries mildly toxic to humans, causing diarrhoea and vomiting. Eaten by bears. Used medicinally by Native Americans for a variety of conditions. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Eranthis hyemalis Salisb. Ranunculaceae Winter Aconite Distribution: Europe. The reason it was called Winter aconite and linked to Aconitum napellus as being just as poisonous is because plants were classified according to leaf shape in the 16th century. L'Obel's Stirpium adversaria nova (1571) and Plantarum seu stirpium historia (1576) (with a full page illustration on page 384 showing Eranthis and Aconitum together) along with the knowledge that related plants have similar medical properties caused the belief that Eranthis are as poisonous as Aconitum. They are both in Ranunculaceae and while Eranthis (like all Ranunculaceae)is toxic if eaten, it does not contain the same chemicals as Aconitum. Caesalpino (Ekphrasis, 1616) pointed out the error in classifying according to leaf shape and recommended flower shape. It contains pharmacologically interesting chemicals such as khellin, also present in Ammi visnaga. This is a vasodilator but quite toxic, but can be converted into khellin analogues such as sodium cromoglicate – used as a prophylaxis against asthma attacks – and amiodarone which has anti-arrhythmia actions so is used for atrial fibrillation and other arrhythmias. It is endangered and protected in the wild (Croatia) because of over-collecting for horticulture. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Senecio pulcher Hook.&Arn. Asteraceae Distribution: South America. It has not attracted attention as a medicinal or toxic plant but members of the genus Senecio contain pyrrolizidine alkaloids that are toxic to the liver and may cause liver cancer. A traditional Chinese medicine (TCM) product, Qianbai Biyan Pian, contains Senecio scandens which contains the unsaturated pyrrolizidine alkaloids, senecionine and seneciphylline. This is now a banned drug. (Safety of Herbal Medicinal Products, July 2002, Medicines Control Agency). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Cynara cardunculus L. Asteraceae. Cardoon, Globe Artichoke, Artechokes, Scolymos cinara, Cynara, Cinara. Distribution: Southern Europe and North Africa. Lyte (1576) writes that Dodoens (1552) could find no medical use for them and Galen (c.200 AD) said they were indigestible unless cooked. However he relates that other authors recommend that if the flower heads are soaked in strong wine, they 'provoke urine and stir up lust in the body.' More prosaically, the roots boiled in wine and drunk it cause the urine to be 'stinking' and so cures smelly armpits. He adds that it strengthens the stomach so causing women to conceive Male children. He goes on to say that the young shoots boiled in broth also stir up lust in men and women, and more besides. Lyte (1576) was translating, I think with elaborations, from the chapter on Scolymos cinara, Artichaut, in Dodoen's Croydeboeck (1552) as L'Ecluse's French translation (1575) does not mention these latter uses, but Dodoen's own Latin translation, the Pemptades(1583), and Gerard's (1633) both do so. It is useful in understanding the history of these translations to realise that Gerard uses, almost verbatim, the translation of the 'smelly armpit' paragraph from Lyte. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Dianella tasmanica Hook.f. Phormiaceae Tasman flax lily. Distribution: Australia. A pretty plant, but also a source of fine fibre. The leaves are used for making baskets and the berries as a dye source. No medicinal use found, but the fruit is an irritant
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Hydrangea quercifolia W.Bartram Hydrangeaceae. Oak-leaved hydrangea. Distribution: South-eastern United States. Beta-dichroine a quinazolinone also called febrifugine from the leaves of hydrangeas is 64-100 times more potent than quinine as an antimalarial in animals, but extremely toxic. A synthesised tolyl derivative, methaqualone (2-methyl-3-o-tolyl-4(3H)-quinazolinone), was found to be a mild hypnotic, and marketed in the sleeping tablet, Mandrax. Widely abused and quickly banned by most countries. Illegal manufacture continues and in South Africa methaqualone is the commonest drug of abuse, mixed with cannabis and smoked. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Arctium lappa L. Asteraceae. Greater Burdock. Distribution: Europe to India and Japan. Dioscorides (Beck, 2003) writes: '... helps those who spit blood and who suffer from abscesses ... plastered on it stems the pains around the joints that stem from twistings. The Leaves are applied beneficially on old ulcers.' Culpeper (1650) writes: ‘Burdanae, etc. Of Bur, Clot-Bur or Burdock, ... helps such as spit blood and matter, bruised and mixed salt and applied to the place, helpeth the bitings of mad dogs. It expels wind, easeth pains of the teeth, strengthens the back, helps the running of the reins, and the whites in women, being taken inwardly.’ The roots contain inulin, which is made into a non-digestible sweetener for diabetics. It has a multitude of uses in herbal medicine, in particular it is a component of a compound called ‘essiac’ that has been widely used as a treatment of cancers in the USA, but which is of no proven benefit. The young roots can be eaten raw or cooked. The seeds are hairy and care should be taken when harvesting them as inhaled they are reported as ‘toxic’. The root is licensed for use in Traditional Herbal Medicines in the UK (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Tanacetum cinerariifolium Sch.Blp. Asteraceae Dalmation chrysanthemum, Pyrethrum, Pellitory, Tansy. Distribution: Balkans. Source of the insecticides called pyrethrins. The Physicians of Myddfai in the 13th century used it for toothache. Gerard called it Pyrethrum officinare, Pellitorie of Spain but mentions no insecticidal use, mostly for 'palsies', agues, epilepsy, headaches, to induce salivation, and applied to the skin, to induce sweating. He advised surgeons to use it to make a cream against the Morbum Neopolitanum [syphilis]. However he also describes Tanacetum or Tansy quite separately.. Quincy (1718) gave the same uses
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Rosa 'Ispahan'
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Trillium sessile L. Trilliaceae Distribution: North America. Various Trilliums were used by Native Americans to stop haematuria, haematemesis, menorrhagia, and to heal ulcers (Milspaugh, 1974). Roots were eaten to treat stiff muscles, and tea from the plant drunk and powdered plant put on joints for rheumatism by the Iroquois (Lewis & Elvin-Lewis, 2003). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Tricyrtis 'Togen' with hoverfly
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Lavatera olbia 'Pink Frills'
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Smilacina racemosa Desf. syn. Maianthemum racemosum (L.)Link Convallariaceae. False Spikenard, False Solomon's Seal, Scurvy berries, Treacle berries. Herbaceous perennial. Distribution: North America. Austin (2004) reports on Native American traditional usage: Cold infusion of the roots for sore eyes (Cherokee)
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Chaenomeles x superba 'Issai White'
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Physalis alkekengi L. Rosaceae Chinese lantern, Winter Cherry, Bladder Cherry. Distribution: C & S Europe, W. Asia to Japan. Culpeper, in his English Physitian of 1652 writes: Winter Cherry ... are of great use in physic ...’ and recommends them for almost all kidney and urinary problems. In particular he seems to advocate the use of green berries in beer, for preventing kidney stones lodging in the ureters. It is called ‘aikakengi’ in the College’s Pharmacopoeia Londinensis of 1618. Belonging to the family Solanaceae, all its parts are poisonous except the ripe fruit. The green fruit and the rest of the plant contain atropinic compounds and will produce a dry mouth, rapid heart beat, hallucinations, coma and death if enough is taken. As the atropine is only present in the unripe fruit eating one will make the mouth go dry (and it has the most unpleasant taste), but it will also relax the smooth muscle in the wall of the ureter which helps passage of ureteric stones. Culpeper’s observations on its usefulness are supported by more modern observations. When ripe, the orange fruit inside its skeletal outer ‘lantern’ is edible, free of atropine, and delicious. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Pulmonaria officinalis L. Boraginaceae Distribution: Europe. Pulmonaria or Lungwort are names for a lichen and a perennial plant in the Boraginaceae. This is the latter. Lyte (1578) has a woodcut of our plant and also calls it Sage of Jerusalem and says it is of 'no particular use in physicke, but is much used in meates and salads with eggs, as is also Cowslippes and Primroses, whereunto in temperature it is much alike.' He lists and describes the lichen separately. Culpeper (1650) said he found many sorts of lunguewort in perusing Authors ' Pulmonari, arborea and Symphytum maculosum [and the latter is our plant, the others the lichen] and that they 'helpe infirmities of the lungues, as hoarseness, coughs, wheezing, shortnesse of breath etc.' Coles (1657) who espouses the Doctrine of Signatures in a way unrivalled by any other English author, might have been expected to confirm the concept that the mottled leaves looked like the cut surface of a lung which indicates their purpose, but he only mentions the lungwort which is a lichen. However, Porta's beautiful book on the Doctrine, Phytognomica (1588), is clear that the plant called Pulmonaria with hairy leaves like a bugloss, spotted white with purple flowers, commonly called 'cynoglossa' [with a woodcut which could be Pulmonaria officinalis] indicate its use for ulcerated lungs, spitting blood, shortness of breath and asthma equally with the lichen with the same name. Lobel & Pena (1570) call it 'PULMONARIA, masculosa folia Borrago. floribus Primula veris, purpureis [PULMONARIA spotted, Borage-leaved, flowers like Primula veris - Cowslips - purple]' and say that women mix the leaves with a little broth and make it into an omelette for lung disorders and to strengthen the heart.. Lobel (1576) calls it Maculosa Pulmonaria and describes a white flowered form with a good woodcut. Gerard (1633) uses the same woodcut as Lobel and calls it Pulmonatia foliis Echii, Buglosse Cowslips with red flowers, and a woodcut of a narrow leaved plant as Pulmonaria masculosa, Spotted Cowslips of Jerusalem with red, blue and purple flowers and says 'the leaves are used among pot-herbes. The roots are aso thought to be good against the infirmities of ulcers of the lungs...'. Quincy (1718) writes: '... it has a glutinous juice ... and heals ulcers and erosions. It is commended in coughs and spitting of blood but is little used either in the Shop or Prescriptions'. Not used in modern medicine. It is in the family Boraginaceae whose species are often rich in pyrrolizidine alkaloids that cause liver toxicity and liver cancers, but levels in Pulmonaria officinalis may not be significant. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Matthiola incana (L.)W.T.Aiton Brassicaceae Distribution: The genus name commemorates Pietro Andrea Mattioli (1500/1–77), physician and botanist, whose name is Latinised to Matthiolus.. Incana means hoary or grey, referring to the colour of the leaves. Mattioli's commentaries on the Materia Medica of Dioscorides were hugely popular. Matthiola incana was first described by Linnaeus as Cheiranthus incanus, being changed to Matthiola by William Aiton, at Kew, in 1812. It is in the cabbage family. Commercial seed packets contain a mixture of single and double forms. The latter are sterile, but selective breeding has increased the proportion of double forms from the seed of single forms to as much as 80%. ‘Ten week stocks’ are popular garden annuals, flowering in the year of sowing, whereas ‘Brompton stocks’ (another variety of M. incana) are biennials, flowering the following year. Gerard (1633), called them Stocke Gillofloure or Leucoium, and notes the white and purple forms, singles and doubles. About their medicinal value he writes ‘not used in Physicke except among certain Empiricks and Quacksalvers, about love and lust matters, which for modestie I omit’. The thought of a member of the cabbage family being an aphrodisiac might encourage the gullible to take more seriously the government’s plea to eat five portions of vegetable/fruit per day. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Cytisus scoparius (L.) Link Fabaceae. Common broom, Genista. Distribution: Western and central Europe. Culpeper (1650) writes: 'Genista. Broom: … clense and open the stomach, break the stone in the reins [kidneys] and bladder, help the green sickness [anaemia]. Let such as are troubled with heart qualms or faintings, forbear it, for it weakens the heart and spirit vital' and in respect of the flowers he writes: 'Broome-flowers, purge water, and are good in dropsies [now regarded as heart failure with fluid retention].' Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Perovskia atriplicifolia 'Blue Spire'
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Ajuga reptans 'Pink Elf'
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Rosa nitida Willd. Rosaceae. Shining rose. Distribution: North-eastern North America. Nitida is Latin for shining, referring to the shiny leaves. The seed heads contain vitamin C. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Prunus mume Siebold & Zucc. Rosaceae Chinese Plum, Japanese Apricot. Distribution: Eastern Asia. The fruit is used to flavour alcohol and used as a digestive to improve appetite. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Catharanthus roseus (L.)G.Don Apocynaceae. Madagascar Periwinkle Distribution: Madagascar. It is the source of vincristine and vinblastine, which impair cell multiplication by interfering with microtubule assembly, causing metaphase arrest and are effective medications for leukaemias, lymphomas and some solid tumours. The mortality from childhood leukaemia fell from 100% to 30% once it was introduced - not a drug that could ethically be tested by double-blind trials. These chemicals were initially discovered by investigators in 1958 who were looking for cures for diabetes so tested this plant which was being used in the West Indies to reduce blood sugar levels. There are 70 different alkaloids present in this plant, and some - catharanthine, leurosine sulphate, lochnerine, tetrahydroalstonine, vindoline and vindolinine - lower blood sugar levels. However, the toxicity of this plant is such that this is not a plant to try at home for diabetic management. The vincristine content of the plant is 0.0003%, so two kilograms of leaf are required to produce sufficient vincristine for a single course of treatment for a child (6gm). Fortunately it is a vigorous weed and easy to grow in the tropics. Artificial synthesis has now been achieved. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Epimedium grandiflorum 'Lilafee'
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Rodgersia aesculifolia Batalin Saxifraginaceae Chestnut-leaved Rodgersia. Herbaceous perennial. Distribution: Northern China. Named for Rear Admiral John Rodgers (1812-1882), American naval officer who commanded the Pacific expedition 1852-1856 when the genus was first discovered. Used as a Traditional Chinese Medicine for rheumatism, bronchitis, dysentery, asthma, and gastritis. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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