concept

Zebrafish neural tube, rotating

Human metaphase, translocation, cosmid probe

Translocation shown using centromere probes

Turner's syndrome, centromere & cosmid probe

Neural tube of zebrafish embryo, colour

Whole arm translocation, centromere probes

Duchenne muscular dystrophy control, FISH

Prader Willi & Angelman's syndromes - probes

Aniridia + translocation, FISH & cosmid prob

Neural tube of zebrafish embryo, movie,color

Human chromosomes highlighted by fluorescent
probes that bind to specific sequences of DNA.
This patient has Turner's syndrome and a
45,X/46,Xr(X) mosaic karyotype. The X chromosome
centromere probe (green) shows that the small ring
chromosome is of X origin and the XIST cosmid
(red) shows that XIST is deleted in this r(X).
(See also B0000316C)
Image by Dr John Crolla.

Turner's stndrome, centromere & cosmid probe

Confocal image of zebrafish embryo (red), showing neural
tube. Image taken using Zeiss LSM 510 Confocal
Microscope.

Neural tube of zebrafish embryo (red)

Confocal images of zebrafish embryo,
showing neural tube. Image taken using Zeiss LSM
510 Confocal Microscope. Neural tissue shows
green.

Neural tube of zebrafish embryo, green

Confocal images of zebrafish embryo, showing neural tube. Image taken using Zeiss LSM
510 Confocal Microscope. Computer-enhanced
colouring, neural tissue green/yellow, background
tissue deep blue, background mauve.

Human chromosomes from a patient with Hereditary
Liability to Pressure Palsy (a lesion of a spinal
root or peripheral nerve resulting from
compression). There is a deletion in chromosome 17
(17p11.2), which has been highlighted using a
fluorescent cosmid probe (red) from the PMP gene.
The chromosome 11 centromeres are green. The
chromosomes have been highlighted with fluorescent
probes that bind to specific sequences of DNA.
Image by Dr John Crolla.

Pressure palsy, deletion c'some 17, cosmid

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FISH

Images

Catalogue

Turner's stndrome, centromere & cosmid probe

Neural tube of zebrafish embryo (red)

Neural tube of zebrafish embryo, green

Neural tube of zebrafish embryo, colour

Pressure palsy, deletion c'some 17, cosmid

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FISH

Images

Catalogue

Turner's stndrome, centromere & cosmid probe

Neural tube of zebrafish embryo (red)

Neural tube of zebrafish embryo, green

Neural tube of zebrafish embryo, colour

Pressure palsy, deletion c'some 17, cosmid

Wellcome Collection

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