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Turner's stndrome, centromere & cosmid probe

Wessex Reg. Genetics Centre
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Credit: Turner's stndrome, centromere & cosmid probe. Credit: Wessex Reg. Genetics Centre. Attribution 4.0 International (CC BY 4.0)

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Human chromosomes highlighted by fluorescent probes that bind to specific sequences of DNA. This patient has Turner's syndrome and a 45,X/46,Xr(X) mosaic karyotype. The X chromosome centromere probe (green) shows that the small ring chromosome is of X origin and the XIST cosmid (red) shows that XIST is deleted in this r(X). (See also B0000316C) Image by Dr John Crolla.


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