Pressure palsy, deletion c'some 17, cosmid

Human chromosomes from a patient with Hereditary Liability to Pressure Palsy (a lesion of a spinal root or peripheral nerve resulting from compression). There is a deletion in chromosome 17 (17p11.2), which has been highlighted using a fluorescent cosmid probe (red) from the PMP gene. The chromosome 11 centromeres are green. The chromosomes have been highlighted with fluorescent probes that bind to specific sequences of DNA. Image by Dr John Crolla.