Human karyotype showing translocation between chromosomes 14 and 21, t(14;21). This is a balanced translocation - the cell retains a normal complement of genetic information.

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Human karyotype showing translocation between chromosomes 14 and 21, t(14;21). This is a balanced translocation - the cell retains a normal complement of genetic information. Wessex Reg. Genetics Centre. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.