concept

Human bronchus, hyperplasia of goblet cells. SEM

Balanced translocation 45,XY,t(13;14)

Small blood vessel in alveoli, SEM

Human cancer cell

Xenopus cancer kidney cells, prometaphase

Bronchus, goblet cell hyperplasia, SEM

Unbalanced translocation 46,XY,t(14;21)

Human HeLa cancer cells, prometaphase

Human HeLa cancer cell in early anaphase of mitosis

Human HeLa cancer cells, mitosis

A deconvolved wide-field fluorescence microscope image of human HeLa cancer cells undergoing mitosis - various stages shown - bottom left, metaphase; top anaphase; bottom right telophase and far right early interphase. The chromosomes show up white with a DAPI stain. The cytoskeleton/spindle microtubules are blue/purple. The red is Aurora B, a protein kinase involved in the polymerisation/depolymerisation of microtubules during mitosis.

Fluorescent micrograph showing human osteosarcoma cells grown in culture. Osteosarcoma is the most common form of bone cancer and occurs due to an error in the growth of osteoblast cells, the cells that are responsible for generating new bone tissue. 



In this image the contrast has been inverted and the microtubules are shown in black. Microtubules are an important component of the cell’s cytoskeleton, composed of a single type of protein, called tubulin, microtubules function to determine cell shape and are dynamic structures involved in a variety of cell movements.



This image was taken using wide field fluorescent microscopy and created by stitching 24 individual images together.

Human osteosarcoma cells

Fluorescent micrograph showing human osteosarcoma cells grown in culture. Osteosarcoma is the most common form of bone cancer and occurs due to an error in the growth of osteoblast cells, the cells that are responsible for generating new bone tissue. 



In this image the microtubules are stained in orange and the cell nuclei stained green. Microtubules are an important component of the cell’s cytoskeleton, composed of a single type of protein, called tubulin, microtubules function to determine cell shape and are dynamic structures involved in a variety of cell movements.

This image was taken using wide field fluorescent microscopy and created by stitching 24 individual images together.

Metaphase spread of normal human male chromosomes, showing Y-banding. Light microscope.

Normal human male metaphase, Y banding

Inversion in the X chromosome 46,X,inv(X)9p21.2?q22.3. One of this pair of human X chromosomes contains a segment that has been broken off then rejoined the opposite way round.

Inversion in X chromosome

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Human

Images

Catalogue

Human HeLa cancer cells, mitosis

Human osteosarcoma cells

Human osteosarcoma cells

Normal human male metaphase, Y banding

Inversion in X chromosome

Wellcome uses cookies.

Human

Images

Catalogue

Human HeLa cancer cells, mitosis

Human osteosarcoma cells

Human osteosarcoma cells

Normal human male metaphase, Y banding

Inversion in X chromosome

Wellcome Collection

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