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Various items from medical and pharmaceutical journals, and newspapers, on clinical trials of Tercinin (patulin) and the common cold.

Wellcome Foundation Ltd

Therapeutic Research Corporation

Secretary's files

1 file Cuttings, some adhered to backing sheets.

"Penicillin Press Cuttings - relative to TRC's letter to <i>The Times</i>, published 12 February 1944"

"Press Cuttings General"

"Chemical Press Cuttings (General)"

"Vivicillin Press Cuttings"

"Dr Petrow's Spare Experimental Details"

"Mould Metabolic Products Reports"

"Mould Metabolic Products Reports" - record of circulation

"Equipment for research workers"

"Publication of Penicillin Chemical Reports"

"Medical Research Council Committee for Penicillin Synthesis"

"Petrow Reports"

"Correspondence re Petrow Reports"

"Pharmacological Sub-Committee: Reports"

"Sulphetrone"

"Coronary Dilators"

Colonial Products Research Council: Annual Reports and reprinted papers

"Research General"

"Supplies of Penicillin for Member Companies"

"TRC Penicillin Synthesis Committee, Minutes and correspondence"

"Penicillin Conference Reports"

"Correspondence relating to Compound No. 209"

Correspondence between Dr Hartley and Dr J N Ashley (May & Baker Ltd)

"Penicillin Chemical Progress Reports" (Boots Pure Drug Co Ltd and May & Baker Ltd)

Letter, Dr Hartley to Dr T H Mead

Correspondence between Dr Hartley and Dr F A Robinson (Glaxo Laboratories Ltd)

"Pharmacological Sub-Committee: memoranda"

Correspondence between Dr Hartley and Dr E Lester Smith (Glaxo Laboratories Ltd)

Correspondence between Dr Hartley and Professor A R Todd (University of Manchester)

Correspondence between Dr Hartley and Dr D A Peak (Boots Pure Drug Co Ltd)

Correspondence between Dr Hartley and Wellcome Physiological Research Laboratories

Correspondence between Dr Hartley and Board Members

Correspondence between Dr Hartley and Dr W Bradley (The British Drug Houses Ltd)

Correspondence between Dr Hartley and Dr W R Boon of Imperial Chemical (Pharmaceuticals) Ltd

"TRC Outside Consultants: Professor H Raistrick"

"TRC Outside Consultants: Sir Robert Robinson"

"TRC Outside Consultants: Professor I M Heilbron"

"TRC Outside Consultants: Dr V A Petrow"

"TRC Outside Consultants: Dr Birkenshaw"

"TRC Outside Consultants: Miscellaneous"

"TRC staff: correspondence with Dr Petrow re his team"

"TRC staff: correspondence with Queen Mary College re Dr Petrow and his team"

"TRC staff: Dr Petrow's assistants"

TRC staff: Albert Courts, research worker under Dr Petrow

TRC staff: Brian Hollingsworth, research worker under Dr Petrow

TRC staff: H J Kahn, research worker under Dr Petrow

TRC staff: E L Rewald, research worker under Dr Petrow

TRC staff: Joshua Saper, research worker under Dr Petrow

TRC staff: B Sturgeon, research worker under Dr Petrow

"TRC staff: general correspondence with Petrow re programme, chemicals etc"

"TRC staff: Professor Heilbron's Group, Imperial College"

"TRC staff: Heilbron's patents"

Fusaria research at Imperial College (Professor Heilbron)

TRC staff: J A Elvidge, research worker under Professor Heilbron

TRC staff: Dr Ronald Bentley, research worker under Professor Heilbron

TRC staff: Dr A H Cook, research worker under Professor Heilbron

TRC staff: Dr John Reynolds Catch, research worker under Professor Heilbron

TRC staff: G Harris, research worker under Professor Heilbron

"TRC staff: laboratory expenses, bench fees etc"

"TRC staff: Professor Raistrick's assistants"

"TRC staff: collaboration with Dr J H Birkinshaw"

"TRC staff: Dr A H Campbell (Glaxo Laboratories Ltd)"

"TRC staff: Sir Robert Robinson's group"

"TRC staff: negotiations with Professor J H Burn"

"TRC staff: negotiations with Professor J H Gaddum"

"TRC staff: negotiations with Dr H A Krebs"

"TRC staff: negotiations with Professor W H Linnell"

"TRC staff: negotiations with Professor M Stacey"

"TRC staff: negotiations with Professor A R Todd"

"TRC staff: negotiations with Professor Wilson Smith"

"TRC staff: correspondence with Dr E Nassau"

"TRC staff: correspondence re honoraria"

"Miscellaneous" correspondence

Trade mark applications for Tercin (No. 624200) and Tercinin (No. 624201)

Trade mark application for Tercinin (Class 1, No. 629870)

Overseas trade mark applications for Tercinin: correspondence with patent agents

Trade mark registration of Tercinin in Argentine

Trade mark registration of Tercinin in Australia

Abandoned trade mark registration of Tercinin in Brazil

Abandoned trade mark registration of Tercinin in Canada

Trade mark registration of Tercinin in Chile

Trade mark registration of Tercinin in Colombia

Trade mark registration of Tercinin in Egypt

Trade mark registration of Tercinin in Eire

Trade mark registration of Tercinin in India

Trade mark registration of Tercinin in New Zealand

Trade mark registration of Tercinin in South Africa

Trade mark registration of Tercinin in Uruguay

Tercinin correspondence

Trade mark application for Teracin (No. 624199)

Notes on trade mark application for "Terce"

Tercinin production reports

"Tercinin: general correspondence and reports"

Clinical Advisory Sub-Committee correspondence

Clinical Advisory Sub-Committee Minutes

"Disposals of Tercinin" (by British Drug Houses Ltd and Boots Pure Drug Co Ltd)

Patulin: published papers

Patulin: correspondence concerning published papers

"Biological examination of chemical products: correspondence"

Lists of Petrow compounds and tuberculostatic compounds

Register Forms for various compounds

"Details of Compounds submitted for Biological Examination"

"Compounds sent for testing" by TRC member companies

Research Executive consent for publication and PhD submission

Various loose papers belonging to L G Matthews (TRC Secretary)

General Penicillin Committee (Ministry of Supply): penicillin production correspondence

"Visit of Dr Hawes (Wellcome Foundation) and Dr Boon (ICP) to USA"

Boon and Hawes, "Report on Penicillin Research and Production in the United States of America, March-April 1943"

Minutes to General Penicillin Committee

General Penicillin Committee: First Annual Report

"Penicillin Trade Mark registrations in Argentine, Uruguay, Central and South America and other countries"

"Sulphetrone trade mark registrations (including patents)"

"Orders for chemicals and intermediates from member companies and consultants"

"Requests for chemicals from Professor W H Linnell"

"Estimated Requirements for Intermediates"

"Cost of Benzyl Penicillamine"

Correspondence with The Dyson Perrins Laboratory (Oxford) concerning chemical supplies

"Estimation of penicillin": correspondence

L G Matthews (TRC Secretary): correspondence

V Petrow, "New syntheses of heterocyclic compounds.  Part XI.  4-Azafluorenones"

Association of British Chemical Manufacturers: Minutes of the Joint Chemical Committee on Patents

Association of British Chemical Manufacturers: patent law reform

Patent Application 13242/41: "Improvements relating to bacteriostatic substances" (Notatin)

Correspondence concerning overseas patent applications for "Acid Pencillin" (Notatin)

Abandoned Patent Applications 6720/42, 6721/42, and 6722/42

Patent Application no. 8189/42 (Notatin)

Patent Application no. 8189/42: correspondence concerning overseas applications

Patent Application 8464/42 (Chemical Chromatography)

Patent Application 5838/44 (Thiosulphate Process)

Patent Application 5838/44: correspondence concerning overseas patent applications

Patent Application 8424/44 (Penicillamine Hydrolysis)

Patent Application 9150/44 (The synthesis of heterocyclic organic compounds containing sulphur)

Patent Application 2291/45 (The synthesis of organic compounds)

Patent Applications 9150/44 and 2291/45: correspondence concerning overseas patent applications

Patent application 12127/44 (The preparation of styryl-type compounds)

Patent Application 12946/44 (The preparation of oxazolone derivatives)

Patent Application 13203/44 (Dinitrochloro-pyridine series)

Patent Application 15145/44 (Carbinol bases)

Patent Application 15770/44 (The preparation of lactones containing nitrogen)

Patent Application 20978/44 (Penicillamine synthesis)

Patent Application 20978/44: correspondence concerning overseas patent applications

Patent Application 22204/44 (Penicillamine racemization)

Patent Applications 22204/44 and 12449/45: corresponence concerning overseas patent applications

"Research Programmes of Constituent Companies"

Patent Application 8464/42 (Chromatographic adsorption)

Patent Application 8464/42: correspondence concerning overseas patent applications

Patent Application 8464/42: correspondence concerning Swedish patent application

Patent Application 8464/42: correspondence concerning Argentine patent application

Patent Application 8464/42: correspondence concerning South African patent application

Patent Application 8464/42: correspondence concerning Australian patent application

Patent Application 8464/42: correspondence concerning Swiss patent application

Patent Application 8464/42: correspondence concerning Indian patent application

Patent Application 8464/42: correspondence concerning Canadian patent application

"Financial & Legal: A, Research Expenses"

"Financial & Legal: B, Publicity Expenses"

"Financial & Legal: C, Experimental Expenses"

"Financial & Legal: D, TRC Experimental Production - Tercinin"

"Financial & Legal: E, TRC Experimental Production - Penicillin"

"Financial & Legal: F, Biological Standard - Serum Gonadotrophin"

"Financial & Legal: G, Subsidiary Standard Neoarsphenamine (May and Baker)"

"Financial & Legal: H, Experimental Expenditure - TRC Compound 245"

"Financial & Legal: I, Experimental Expenditure Sulphetrone"

"Financial & Legal: L, TRC 388"

Photographs produced for TRC Penicillin booklet (Dr Hartleys' photographs)

"Patents Sub-Committee"

"Assignment of TRC Patents to Medical Research Council"

"Patents General: disclosure of information"

Minutes to Patents Sub-Committee

"Summary of Patent Applications Regarding Penicillin"

"TRC Patent Policy"

"Medical Patents for TRC: Deputation to Sir John Anderson"

"Imperial Chemical (Pharmaceuticals) Ltd - patents"

Patents: "CIBA Opposition"

Patent Applications 11729/42 and 14018/42 (Penicillin)

'Patent Application 16021/42 (Notatin)

Patent Application 15284/43 (Tercinin production)

Patent Application 15284/43: US patent application

Patent Application 15934/43 (Synthesis of organic compounds)

Patent Application 20439/43 (Hydrogenated penicillin)

Patent Application 20439/43: various overseas applications

Patent Application 961/44 (Penicillamine intermediate)

Patent Application 3130/44 (Cysteines acid addition)

Patent Application 3130/44: US patent application

Patent Application 3130/44: patent applications in Australia, Canada, India, New Zealand, and South Africa

Patent Application 2597/44 (Sulphur compounds)

Patent Application 2597/44: US patent application

Patent Application 2597/44: patent applications in Australia, Canada, India, New Zealand, and South Africa

"Assignments of Patents to TRC"

"Correspondence relating to TRC Patents Sub-Committee Minutes"

Press cuttings concerning Tercinin (patulin) and the common cold

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Press cuttings concerning Tercinin (patulin) and the common cold

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