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RESEARCH RELATING TO MULTIPLE SCLEROSIS

RHST's publications

Reprints

'Vitamin B1 and the Kidney', RHST, Journal of Physiology, vol 81

'Pyruvic Acid in Metabolism of Brain', R A Peters and RHST, Biochemical Journal, vol 28, no 3, pp 916-925

'The Action of Crystalline Vitamin B1 on the Respiration of Polyneuritic Tissues in vitro', RHST, Biochemical Journal, vol 28, no 3, pp 909-915

'Blood Pyruvate in Vitamin B1 Deficiency', RHST and Robert Eugene Johnson

'A note on the Level of Carbonyl Compounds in Human Blood', R E Johnson, A P Meiklejohn, R Passmore and RHST, The Biochemical Journal, vol 29, no 11, pp 2506-2509

'The Decomposition of Yeast Nucleic Acid by a Heat-Resistant Enzyme', Rene J Dubos and RHST, The Journal of Biological Chemistry, vol 124, no 2, pp 501-510

'The Isolation of Nucleic Acid and Nucleoprotein Fractions from Pneumococci', RHST and Rene J Dubos, The Journal of Biological Chemistry, vol 125, no 1, pp 65-74

'Production of Experimental Osteomyelitis in Rabbits by Intravenous Injection of Staphylococcus Aureus', RHST and R J Dubos, Journal of Experimental Medicine, vol 68, no 2, pp 191-206

'The Ultraviolet Absorption Spectra of Fractions Isolated from Pneumococci', G I Lavin, RHST and R J Dubos, Journal of Biological Chemistry, vol 125, no 1, pp 75-78

'Sulphur-containing Amino-Acids and Jaundice', R A Peters, A J King, RHST, D I Williams and C S Nicol, Nature, vol 153, p 773

'Studies on Copper Metabolism in Demyelinating Diseases of the Central Nervous System', B M Mandlebrote, M W Stanier, RHST and M N Thruston, Brain, vol 71, part II, pp 212-228

'Serum Copper Levels in Pregnancy and PreEclampsia', RHST and D W Watson, Journal of Clinical Pathology, vol 2, no 3, pp 193-196

'Nature of Placental Cholinesterase', M G Ord and RHST, Nature, vol 165, p 927

'The Distribution of Cholinesterase Types in Mammalian Tissues', M G Ord and RHST, The Biochemical Journal, vol 46, no 3, pp 346-352

'Blood Pyruvate Estimations in the Diagnosis and Treatment of Polyneuritis', C L Joiner, B McArdle and RHST, Brain, vol 73, part 4, pp 431-452

'A Discussion on the Action of Local Hormones', [including a contribution from RHST], Proceedings of the Royal Society, vol 137, pp 281-320

'Pyruvate Tolerance in Peripheral Neuropathy and other Conditions', C L Joiner, RHST and D Watson, Guy's Hospital Reports, vol 99, no 1, pp 62-76

'The Occurrence and Distribution of Mono-amine Oxidase in Blood Vessels', RHST and A Tickner, Journal of Physiology, vol 115, no 1, pp 34-40

'The Nitroprusside Method for the determination of Blood Glutathione', RHST and D Watson, Journal of Clinical Pathology, vol 5, no 1, pp 25-29

'The Diagnostic Value of Serum Iron Studies in Haemochromatosis: Observations on Seven Patients', J C Houston and RHST, Quarterly Journal of Medicine, no 82, pp 215-224

'The Inhibitory Action of Tri-Ortho-Cresyl Phosphate on Cholinesterases', C J Earl and RHST, British Journal of Pharmacology and Chemotherapy, vol 7, no 2, pp 261-268

'Some Biochemical Features of the Peripheral Neuropathies', RHST, Proceedings of the Royal Society of Medicine, vol 45, no 10, pp 664-667

'Pseudo-Cholinesterase Activity in the Central Nervous System', Margery G Ord and RHST, The Biochemical Journal, vol 51, no 2, pp 245-251

'Cholinesterases and Anti-Cholinesterases', RHST, Lectures on the Scientific Basis of Medicine, Vol II, pp 165-181

'Cholinesterases', RHST, British Medical Bulletin, vol 9, no 2, pp 138-141

'Serum Iron Estimations in the Diagnosis of Haemochromatosis', J C Houston and RHST, Guy's Hospital Reports, vol 102, no 4, 355-359

'An Explanation for the Heightened Vascular Reactivity of the Denervated Rabbit's Ear', J Armin, R T Grant, RHST and A Tickner, Journal of Physiology, vol 121, no 3, pp 603-622

'Cholinesterase Activity of Arteries', RHST and A Tickner, Journal of Physiology, vol 121, no 3, pp623-628

'Separation and Estimation of Blood Keto Acids by Paper Chromatography', M F S El Hawary and RHST, The Biochemical Journal, vol 53, no 3, pp 340-347

'Cholinesterase Activity of Human Skin', I A Magnus and RHST, British Journal of Dermatology, vol 66, no 5, pp 163-173

'Cholinesterase Inhibition by Lysergic Acid Diethylamide', RHST, A Tickner and G R Webster, Proceedings of the Biochemical Society, vol 58, part 2, p 19

'A Note on the Chromatographic Identification of Blood Keto Acids in Animals Poisoned with Arsenite and Alloxan', M F S El Hawary and RHST, The Biochemical Journal, vol 58, no 4, pp 518-520

'The Localisation of Pseudo-Cholinesterase Activity in Nervous Tissue', J B Cavanagh and RHST, Journal of Experimental Physiology, vol 39, pp 185-197

'Anticholinesterases', RHST, Chemistry and Industry, pp 749-751

'The Effect of Cholinesterase Inhibitors on the Leakage of Potassium from Brain Slices', K P Strickland and RHST, Proceedings of the Biochemical Society, vol 58, part 2, pp 20

'The Action of Lysergic Acid Diethylamide on Mammalian Cholinesterases', RHST, A Tickner and G R Webster, British Journal of Pharmacology and Chemotherapy, vol 10, no 1, pp 61-65

'Blood Keto Acid Levels during Intoxication with Inhibitors of Carbohydrate Metabolism', M F S El Hawary, The Biochemical Journal, vol 61, no 2, pp 348-352

'On the Mechanism of the Potassium Loss from Brain Slices induced by Cholinesterase Inhibitors', K P Strickland and RHST, The Biochemical Journal, vol 60, no 3, pp 468-475

'Serum Cholinesterase Levels in Diabetes Mellitus', RHST and J R Trounce, The Lancet, pp 656-658

'Cholinesterase Levels in the Skin in Cholinogenic Urticaria and Pruritus', I A Magnus and RHST, The British Journal of Dermatology, vol 68, no 9, pp 283-289

'Hydrolysis of Phosphoryl Choline and Related Esters by the Phosphomonoesterases of Animal Tissues', K P Strickland, RHST and G R Webster, Archives of Biochemistry and Biophysics, vol 64, no 2, pp 498-505

'The Action of Phosphatases of Human Brain on Lipid Phosphate Esters', K P Strickland, RHST and G R Webster, Journal of Neurology, Neurosurgery and Psychiatry, vol 19, pp 12-16

'Esterases, Lipases and Phosphatases of the Nervous System', RHST, Guy's Hospital Reports, vol 105, no 1, pp 93-107

'The Effects of Anticholinesterases on Oxidative Phosphorylation in Brain, and their relation to Potassium Loss and Nerve Degeneration', K P Strickland, RHST and G R Webster, The Biochemical Journal, vol 62, no 3, pp 512-517

'Biochemical Disorders in Peripheral Neuropathies', RHST, Proceedings of the 3rd International Congress of Biochemistry, Brussels, 1955, pp 29-36

'Clearing Action of Lysolecithin on Brain Homogenates', G R Webster, Nature, vol 180, pp 660-661

'Glycerylphosphorylcholine Diesterase Activity of Nervous Tissue', G R Webster, E A Marples and RHST, The Biochemical Journal, vol 65, no 2, pp 374-377

'The Effect of Lysolecithin on certain Enzymic Activities of Brain', E A Marples, G R Webster and RHST, Proceedings of the Biochemical Society, vol 67, no 4, p 31

'The Effect of Dimercaprol (BAL) on Blood Sugar and Pyruvate Levels on Diabetes Mellitus', W J Butterfield and RHST, Clinical Science, vol 16, no 4, pp 679-694

'The Effect of Nerve Section on the free Amino Acids of Nervous Tissue', G Porcellati and RHST, Journal of Neurochemistry, vol 1, pp 340-347

'International Commission on Enzymes', O Hoffmann-Oostenhof and RHST, Nature, vol 181, p 452

'Abnormal Pyruvate Metabolism in Diabetes Mellitus', W J H Butterfield, I Kelsey Fry and RHST, Proceedings of the 3rd International Diabetes Federation, Dusseldorf, pp 770-774

'Residual Phospholipase A Activity in Lysolecithin prepared by the Action of Snake Venom on Ovolecithin', E A Marples and RHST, Biochim. Biophys. Acta, vol 30, pp 187-188

'Urinary Excretion of Catecholamines in Phaeochromocytoma and other Abnormal States', RHST and J R Trounce, Guy's Hospital Reports, vol 107, no 4, pp 475-485

'The Liberation of Active Enzymes from Brain Tissue by Lysolecithin', E A Marples, RHST and G R Webster, Journal of Neurochemistry, vol 4, pp 62-70

'Pyruvate Metabolism in Diabetic Neuropathy', RHST, W J H Butterfield and I Kelsey Fry, Proceedings of the Royal Society of Medicine, vol 53, no 2, pp 143-146

'The Distribution of Phospholipase B in Mammalian Tissues', E A Marples and RHST, The Biochemical Journal, vol 74, no 1, pp 123-127

'The Estimation of Phospholipase A Activity in Aqueous Systems', W L Magee and RHST, Biochemical Journal, vol 7, pp 526-534

'The Identification of Lysolecithin in Lipid Extracts of Brain', RHST, R Niemiro and G R Webster, Biochim. Biophys. Acta, vol 40, pp 118-123

'The Action of Lysolecithin and of Snake Venom on Whole-cell Preparations of Brain, Muscle and Liver', M McArdle, RHST and G R Webster, Journal of Neurochemistry, vol 5, pp 135-144

'Neurochemistry', RHST, Annual Review of Biochemistry, vol 29, pp 365-390

'The Distribution of Copper in Human Brain', P J Warren, C J Earl and RHST, Brain, vol 83, part 4, pp 709-717

'Myelinolytic Mechanisms', RHST, Proceedings of the Royal Society of Medicine, vol 54, no 1, pp 30-34

'The Biochemistry of Multiple Sclerosis', RHST, The Scientific Basis of Medicine Annual Review, pp 283-301

'Relative Cholinesterase Levels in Sliced, Minced and Homogenized Preparations of Nervous Tissue', R Pavlin and RHST, Guy's Hospital Reports, vol 100, no 2, pp 168-173

'Classification and Nomenclature of Enzymes and Coenzymes', RHST, Nature, vol 193, no 4822, pp 1227-1231

'Classification and Nomenclature of Enzymes', RHST, Science, vol 137, no 3528, pp 405-408

'The Purification and Properties of Phospholipase A from Human Pancreas', W L Magee, J Gallai-Hatchard, H Sanders and RHST, Biochemical Journal, vol 83, pp 17-25

'The Action of Snake Venoms on the Membrane Permeability of Brain, Muscle and Red Blood Cells', B S Meldrum and RHST, Guy's Hospital Reports, vol 100, no 1, pp 87-97

'The Preparation and Properties of Lysophatidylserine', L Rathbone, W L Magee and RHST, The Biochemical Journal, vol 83, pp 498-502

'Observations on the Presence of Lysolecithin in Nervous Tissues', G R Webster and RHST, Biochimica et Physica Acta, vol 63, pp 38-45

'Some Aspects of Lipid Metabolism in Rats treated with Anti-Insulin Serum', M E Tarrant, RHST and P H Wright, The Biochemical Journal, vol 84, pp 6-10

'The Formation of Lysophosphatides from DiAcyl Phosphatides by Brain Preparations', J Gallai-Hatchard, W L Magee, RHST and G R Webster, Journal of Neurochemistry, vol 9, pp 545-554

'Fatty-acid Composition of Brain Lecithins in Multiple Sclerosis', R W R Baker, RHST and K J Zilkha, The Lancet, pp 26-27

'Cholinesterase and the Nerve Supply to Blood Vessels in the Rabbit's External Ear', R T Grant and RHST, Journal of Anatomy, London, vol 97, no 1, pp 7-22

'The Mode of Action of Human Pancreatic Phospholipase A', G H De Haas, C H T Heemskerke and L M Van Deenenand R W R Baker, J Gallai-Hatchard, W L Magee and RHST, The Biochemical Problems of Lipids, vol 1, pp 244-250

'The International Union of Biochemistry', RHST, ICSU Review, vol 5, pp 142-146

'The Action of Phospholipase A on Purified Phospholipids, Plasma and Tissue Preparations', S A Ibrahim, Hazel Sanders and RHST, Biochemical Journal, vol 93, pp 588-594

'Serum Fatty Acids in Multiple Sclerosis', R W R Baker, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 27, pp 408-414

'Accumulation of Lysolecithin in Rat Brain on Incubation in vitro', G R Webster and RHST, Nature, vol 206, no 4981, pp 296-297

'Platelet Adhesiveness in Multiple Sclerosis', H Payling Wright, RHST and K J Zilkha, The Lancet, pp 1109-1110

'Phospholipase-A Activity of Mammalian Tissues', J Gallai-Hatchard and RHST, Biochimica et Physica Acta, vol 98, pp 128-136

'Action of Phospholipase A on Human Red Cell Ghosts and Intact Erythrocytes', S A Ibrahim and RHST, Biochimica et Biophysica Acta, vol 99, pp 331-341

'The Pathological Chemistry of the Demyelinating Diseases', RHST, The Scientific Basis of Medicine Annual Review, pp 58-73

'Plasma Phospholipids and their Fatty Acid Composition in Multiple Sclerosis', S Montfoort, R W R Baker, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 29, pp 99-102

'Changes in the Amounts of Linoleic Acid in the Serum of Patients with Multiple Sclerosis', R W R Baker, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 29, pp 95-98

'A Biochemical Approach to the Problems of Multiple Sclerosis', RHST(The Jephcott Lecture) , Proceedings of the Royal Society of Medicine, vol 59, no 3, pp 269-276

'Third World Conference on Medical Education', L P LeQuesne and RHST, British Journal of Medical Education, vol 1, no 2, pp 99-102

'Further Studies on Platelet Adhesiveness and Serum Cholesteryl[sic] Linoleate Levels in Multiple Sclerosis', H Sanders, RHST, H Payling Wright and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 31, pp 321-325

'Fatty Acid Composition of Phospholipids from Platelets and Erythrocytes in Multiple Sclerosis', S Gul, A D Smith, RHST, H Paying Wright and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 33, pp 506-510

'Linoleate Metabolism in Multiple Sclerosis', J Belin, N Petter, A D Smith, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 34, pp 25-29

'The Function of a Vitamin: The Legacy of this Concept to Biochemistry', RHST, Biochemical Pharmacology, vol 20, pp 513-517

'The Effect of Fatty Acids and of Albumin on the Action of a Purified Phospholipase-A2 from Cobra Venom on Synthetic Lecithins' A D Smith, S Gul and RHST, Biochemic, et Physica Acta, vol 289, pp 147-157

'Double-blind Trial of Linoleate Supplementation of the Diet in Multiple Sclerosis', J H D Millar, K J Zilkha, M H A Langman, H Payling Wright, A D Smith, J Belin and RHST, British Medical Journal, pp 756-768

'Effect of short term Oral Administration of Sunflower Seed Oil on the Pattern of non-Esterified Fatty Acids in Human Plasma', J Belin, A D Smith and RHST, Clinica Chimica Acta, vol 61, pp 95-98

'Relationship between Plasma and Lymphocyte Linoleate in Multiple Sclerosis', W M Tsang, J Belin, J A Monro, A D Smith, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol, 39, no 8, pp 767-771

'Levels of Linoleate and Arachidonate in Red Blood Cells of Healthy Individuals and Patients with Multiple Sclerosis', S T Homa, J Belin, A D Smith, J A Monro and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 43, no 2, pp 106-110

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'Levels of Linoleate and Arachidonate in Red Blood Cells of Healthy Individuals and Patients with Multiple Sclerosis', S T Homa, J Belin, A D Smith, J A Monro and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 43, no 2, pp 106-110

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