Human HeLa cancer cell, metaphase.

  • Paul Andrews/Univ. Dundee
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Human HeLa cancer cell, metaphase. Paul Andrews/Univ. Dundee. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.

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A deconvolved wide-field fluorescence microscope image of a human HeLa cancer cell in metaphase of mitosis. The chromosomes show whitish blue (DAPI stain for DNA). The microtubules of the cytoskeleton/spindle are blue. The green is Aurora B, a protein kinase involved in the polymerisation/depolymerisation of the microtubules during mitosis. The Red is CENP-F, an outer kinetochore protein that is important for mitosis.

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