work

Galleries and Reading Room

Café

Shop

Library

Our galleries are quietest on weekdays and weekend mornings. At busy times, particularly on Saturdays, you may need to queue for our temporary exhibitions.

We’re undertaking some research with website visitors to learn more about how people find access-related information provided by museums. This survey shouldn't take longer than 10 minutes to complete. Thank you for your time!

Help us organize our website content.

RESEARCH RELATING TO MULTIPLE SCLEROSIS

RHST's publications

Reprints

'Vitamin B1 and the Kidney', RHST, Journal of Physiology, vol 81

'Pyruvic Acid in Metabolism of Brain', R A Peters and RHST, Biochemical Journal, vol 28, no 3, pp 916-925

'The Action of Crystalline Vitamin B1 on the Respiration of Polyneuritic Tissues in vitro', RHST, Biochemical Journal, vol 28, no 3, pp 909-915

'Blood Pyruvate in Vitamin B1 Deficiency', RHST and Robert Eugene Johnson

'A note on the Level of Carbonyl Compounds in Human Blood', R E Johnson, A P Meiklejohn, R Passmore and RHST, The Biochemical Journal, vol 29, no 11, pp 2506-2509

'The Decomposition of Yeast Nucleic Acid by a Heat-Resistant Enzyme', Rene J Dubos and RHST, The Journal of Biological Chemistry, vol 124, no 2, pp 501-510

'The Isolation of Nucleic Acid and Nucleoprotein Fractions from Pneumococci', RHST and Rene J Dubos, The Journal of Biological Chemistry, vol 125, no 1, pp 65-74

'Production of Experimental Osteomyelitis in Rabbits by Intravenous Injection of Staphylococcus Aureus', RHST and R J Dubos, Journal of Experimental Medicine, vol 68, no 2, pp 191-206

'The Ultraviolet Absorption Spectra of Fractions Isolated from Pneumococci', G I Lavin, RHST and R J Dubos, Journal of Biological Chemistry, vol 125, no 1, pp 75-78

'Sulphur-containing Amino-Acids and Jaundice', R A Peters, A J King, RHST, D I Williams and C S Nicol, Nature, vol 153, p 773

'Studies on Copper Metabolism in Demyelinating Diseases of the Central Nervous System', B M Mandlebrote, M W Stanier, RHST and M N Thruston, Brain, vol 71, part II, pp 212-228

'Serum Copper Levels in Pregnancy and PreEclampsia', RHST and D W Watson, Journal of Clinical Pathology, vol 2, no 3, pp 193-196

'Nature of Placental Cholinesterase', M G Ord and RHST, Nature, vol 165, p 927

'The Distribution of Cholinesterase Types in Mammalian Tissues', M G Ord and RHST, The Biochemical Journal, vol 46, no 3, pp 346-352

'Blood Pyruvate Estimations in the Diagnosis and Treatment of Polyneuritis', C L Joiner, B McArdle and RHST, Brain, vol 73, part 4, pp 431-452

'A Discussion on the Action of Local Hormones', [including a contribution from RHST], Proceedings of the Royal Society, vol 137, pp 281-320

'Pyruvate Tolerance in Peripheral Neuropathy and other Conditions', C L Joiner, RHST and D Watson, Guy's Hospital Reports, vol 99, no 1, pp 62-76

'The Occurrence and Distribution of Mono-amine Oxidase in Blood Vessels', RHST and A Tickner, Journal of Physiology, vol 115, no 1, pp 34-40

'The Nitroprusside Method for the determination of Blood Glutathione', RHST and D Watson, Journal of Clinical Pathology, vol 5, no 1, pp 25-29

'The Diagnostic Value of Serum Iron Studies in Haemochromatosis: Observations on Seven Patients', J C Houston and RHST, Quarterly Journal of Medicine, no 82, pp 215-224

'The Inhibitory Action of Tri-Ortho-Cresyl Phosphate on Cholinesterases', C J Earl and RHST, British Journal of Pharmacology and Chemotherapy, vol 7, no 2, pp 261-268

'Some Biochemical Features of the Peripheral Neuropathies', RHST, Proceedings of the Royal Society of Medicine, vol 45, no 10, pp 664-667

'Pseudo-Cholinesterase Activity in the Central Nervous System', Margery G Ord and RHST, The Biochemical Journal, vol 51, no 2, pp 245-251

'Cholinesterases and Anti-Cholinesterases', RHST, Lectures on the Scientific Basis of Medicine, Vol II, pp 165-181

'Cholinesterases', RHST, British Medical Bulletin, vol 9, no 2, pp 138-141

'Serum Iron Estimations in the Diagnosis of Haemochromatosis', J C Houston and RHST, Guy's Hospital Reports, vol 102, no 4, 355-359

'An Explanation for the Heightened Vascular Reactivity of the Denervated Rabbit's Ear', J Armin, R T Grant, RHST and A Tickner, Journal of Physiology, vol 121, no 3, pp 603-622

'Cholinesterase Activity of Arteries', RHST and A Tickner, Journal of Physiology, vol 121, no 3, pp623-628

'Separation and Estimation of Blood Keto Acids by Paper Chromatography', M F S El Hawary and RHST, The Biochemical Journal, vol 53, no 3, pp 340-347

'Cholinesterase Activity of Human Skin', I A Magnus and RHST, British Journal of Dermatology, vol 66, no 5, pp 163-173

'Cholinesterase Inhibition by Lysergic Acid Diethylamide', RHST, A Tickner and G R Webster, Proceedings of the Biochemical Society, vol 58, part 2, p 19

'A Note on the Chromatographic Identification of Blood Keto Acids in Animals Poisoned with Arsenite and Alloxan', M F S El Hawary and RHST, The Biochemical Journal, vol 58, no 4, pp 518-520

'The Localisation of Pseudo-Cholinesterase Activity in Nervous Tissue', J B Cavanagh and RHST, Journal of Experimental Physiology, vol 39, pp 185-197

'Anticholinesterases', RHST, Chemistry and Industry, pp 749-751

'The Effect of Cholinesterase Inhibitors on the Leakage of Potassium from Brain Slices', K P Strickland and RHST, Proceedings of the Biochemical Society, vol 58, part 2, pp 20

'The Action of Lysergic Acid Diethylamide on Mammalian Cholinesterases', RHST, A Tickner and G R Webster, British Journal of Pharmacology and Chemotherapy, vol 10, no 1, pp 61-65

'Blood Keto Acid Levels during Intoxication with Inhibitors of Carbohydrate Metabolism', M F S El Hawary, The Biochemical Journal, vol 61, no 2, pp 348-352

'On the Mechanism of the Potassium Loss from Brain Slices induced by Cholinesterase Inhibitors', K P Strickland and RHST, The Biochemical Journal, vol 60, no 3, pp 468-475

'Serum Cholinesterase Levels in Diabetes Mellitus', RHST and J R Trounce, The Lancet, pp 656-658

'Cholinesterase Levels in the Skin in Cholinogenic Urticaria and Pruritus', I A Magnus and RHST, The British Journal of Dermatology, vol 68, no 9, pp 283-289

'Hydrolysis of Phosphoryl Choline and Related Esters by the Phosphomonoesterases of Animal Tissues', K P Strickland, RHST and G R Webster, Archives of Biochemistry and Biophysics, vol 64, no 2, pp 498-505

'The Action of Phosphatases of Human Brain on Lipid Phosphate Esters', K P Strickland, RHST and G R Webster, Journal of Neurology, Neurosurgery and Psychiatry, vol 19, pp 12-16

'Esterases, Lipases and Phosphatases of the Nervous System', RHST, Guy's Hospital Reports, vol 105, no 1, pp 93-107

'The Effects of Anticholinesterases on Oxidative Phosphorylation in Brain, and their relation to Potassium Loss and Nerve Degeneration', K P Strickland, RHST and G R Webster, The Biochemical Journal, vol 62, no 3, pp 512-517

'Biochemical Disorders in Peripheral Neuropathies', RHST, Proceedings of the 3rd International Congress of Biochemistry, Brussels, 1955, pp 29-36

'Clearing Action of Lysolecithin on Brain Homogenates', G R Webster, Nature, vol 180, pp 660-661

'Glycerylphosphorylcholine Diesterase Activity of Nervous Tissue', G R Webster, E A Marples and RHST, The Biochemical Journal, vol 65, no 2, pp 374-377

'The Effect of Lysolecithin on certain Enzymic Activities of Brain', E A Marples, G R Webster and RHST, Proceedings of the Biochemical Society, vol 67, no 4, p 31

'The Effect of Dimercaprol (BAL) on Blood Sugar and Pyruvate Levels on Diabetes Mellitus', W J Butterfield and RHST, Clinical Science, vol 16, no 4, pp 679-694

'The Effect of Nerve Section on the free Amino Acids of Nervous Tissue', G Porcellati and RHST, Journal of Neurochemistry, vol 1, pp 340-347

'International Commission on Enzymes', O Hoffmann-Oostenhof and RHST, Nature, vol 181, p 452

'Abnormal Pyruvate Metabolism in Diabetes Mellitus', W J H Butterfield, I Kelsey Fry and RHST, Proceedings of the 3rd International Diabetes Federation, Dusseldorf, pp 770-774

'Residual Phospholipase A Activity in Lysolecithin prepared by the Action of Snake Venom on Ovolecithin', E A Marples and RHST, Biochim. Biophys. Acta, vol 30, pp 187-188

'Urinary Excretion of Catecholamines in Phaeochromocytoma and other Abnormal States', RHST and J R Trounce, Guy's Hospital Reports, vol 107, no 4, pp 475-485

'The Liberation of Active Enzymes from Brain Tissue by Lysolecithin', E A Marples, RHST and G R Webster, Journal of Neurochemistry, vol 4, pp 62-70

'Pyruvate Metabolism in Diabetic Neuropathy', RHST, W J H Butterfield and I Kelsey Fry, Proceedings of the Royal Society of Medicine, vol 53, no 2, pp 143-146

'The Distribution of Phospholipase B in Mammalian Tissues', E A Marples and RHST, The Biochemical Journal, vol 74, no 1, pp 123-127

'The Estimation of Phospholipase A Activity in Aqueous Systems', W L Magee and RHST, Biochemical Journal, vol 7, pp 526-534

'The Identification of Lysolecithin in Lipid Extracts of Brain', RHST, R Niemiro and G R Webster, Biochim. Biophys. Acta, vol 40, pp 118-123

'The Action of Lysolecithin and of Snake Venom on Whole-cell Preparations of Brain, Muscle and Liver', M McArdle, RHST and G R Webster, Journal of Neurochemistry, vol 5, pp 135-144

'Neurochemistry', RHST, Annual Review of Biochemistry, vol 29, pp 365-390

'The Distribution of Copper in Human Brain', P J Warren, C J Earl and RHST, Brain, vol 83, part 4, pp 709-717

'Myelinolytic Mechanisms', RHST, Proceedings of the Royal Society of Medicine, vol 54, no 1, pp 30-34

'The Biochemistry of Multiple Sclerosis', RHST, The Scientific Basis of Medicine Annual Review, pp 283-301

'Relative Cholinesterase Levels in Sliced, Minced and Homogenized Preparations of Nervous Tissue', R Pavlin and RHST, Guy's Hospital Reports, vol 100, no 2, pp 168-173

'Classification and Nomenclature of Enzymes and Coenzymes', RHST, Nature, vol 193, no 4822, pp 1227-1231

'Classification and Nomenclature of Enzymes', RHST, Science, vol 137, no 3528, pp 405-408

'The Action of Snake Venoms on the Membrane Permeability of Brain, Muscle and Red Blood Cells', B S Meldrum and RHST, Guy's Hospital Reports, vol 100, no 1, pp 87-97

'The Preparation and Properties of Lysophatidylserine', L Rathbone, W L Magee and RHST, The Biochemical Journal, vol 83, pp 498-502

'Observations on the Presence of Lysolecithin in Nervous Tissues', G R Webster and RHST, Biochimica et Physica Acta, vol 63, pp 38-45

'Some Aspects of Lipid Metabolism in Rats treated with Anti-Insulin Serum', M E Tarrant, RHST and P H Wright, The Biochemical Journal, vol 84, pp 6-10

'The Formation of Lysophosphatides from DiAcyl Phosphatides by Brain Preparations', J Gallai-Hatchard, W L Magee, RHST and G R Webster, Journal of Neurochemistry, vol 9, pp 545-554

'Fatty-acid Composition of Brain Lecithins in Multiple Sclerosis', R W R Baker, RHST and K J Zilkha, The Lancet, pp 26-27

'Cholinesterase and the Nerve Supply to Blood Vessels in the Rabbit's External Ear', R T Grant and RHST, Journal of Anatomy, London, vol 97, no 1, pp 7-22

'The Mode of Action of Human Pancreatic Phospholipase A', G H De Haas, C H T Heemskerke and L M Van Deenenand R W R Baker, J Gallai-Hatchard, W L Magee and RHST, The Biochemical Problems of Lipids, vol 1, pp 244-250

'The International Union of Biochemistry', RHST, ICSU Review, vol 5, pp 142-146

'The Action of Phospholipase A on Purified Phospholipids, Plasma and Tissue Preparations', S A Ibrahim, Hazel Sanders and RHST, Biochemical Journal, vol 93, pp 588-594

'Serum Fatty Acids in Multiple Sclerosis', R W R Baker, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 27, pp 408-414

'Accumulation of Lysolecithin in Rat Brain on Incubation in vitro', G R Webster and RHST, Nature, vol 206, no 4981, pp 296-297

'Platelet Adhesiveness in Multiple Sclerosis', H Payling Wright, RHST and K J Zilkha, The Lancet, pp 1109-1110

'Phospholipase-A Activity of Mammalian Tissues', J Gallai-Hatchard and RHST, Biochimica et Physica Acta, vol 98, pp 128-136

'Action of Phospholipase A on Human Red Cell Ghosts and Intact Erythrocytes', S A Ibrahim and RHST, Biochimica et Biophysica Acta, vol 99, pp 331-341

'The Pathological Chemistry of the Demyelinating Diseases', RHST, The Scientific Basis of Medicine Annual Review, pp 58-73

'Plasma Phospholipids and their Fatty Acid Composition in Multiple Sclerosis', S Montfoort, R W R Baker, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 29, pp 99-102

'Changes in the Amounts of Linoleic Acid in the Serum of Patients with Multiple Sclerosis', R W R Baker, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 29, pp 95-98

'A Biochemical Approach to the Problems of Multiple Sclerosis', RHST(The Jephcott Lecture) , Proceedings of the Royal Society of Medicine, vol 59, no 3, pp 269-276

'Third World Conference on Medical Education', L P LeQuesne and RHST, British Journal of Medical Education, vol 1, no 2, pp 99-102

'Further Studies on Platelet Adhesiveness and Serum Cholesteryl[sic] Linoleate Levels in Multiple Sclerosis', H Sanders, RHST, H Payling Wright and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 31, pp 321-325

'Fatty Acid Composition of Phospholipids from Platelets and Erythrocytes in Multiple Sclerosis', S Gul, A D Smith, RHST, H Paying Wright and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 33, pp 506-510

'Linoleate Metabolism in Multiple Sclerosis', J Belin, N Petter, A D Smith, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 34, pp 25-29

'The Function of a Vitamin: The Legacy of this Concept to Biochemistry', RHST, Biochemical Pharmacology, vol 20, pp 513-517

'The Effect of Fatty Acids and of Albumin on the Action of a Purified Phospholipase-A2 from Cobra Venom on Synthetic Lecithins' A D Smith, S Gul and RHST, Biochemic, et Physica Acta, vol 289, pp 147-157

'Double-blind Trial of Linoleate Supplementation of the Diet in Multiple Sclerosis', J H D Millar, K J Zilkha, M H A Langman, H Payling Wright, A D Smith, J Belin and RHST, British Medical Journal, pp 756-768

'Effect of short term Oral Administration of Sunflower Seed Oil on the Pattern of non-Esterified Fatty Acids in Human Plasma', J Belin, A D Smith and RHST, Clinica Chimica Acta, vol 61, pp 95-98

'Relationship between Plasma and Lymphocyte Linoleate in Multiple Sclerosis', W M Tsang, J Belin, J A Monro, A D Smith, RHST and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol, 39, no 8, pp 767-771

'Levels of Linoleate and Arachidonate in Red Blood Cells of Healthy Individuals and Patients with Multiple Sclerosis', S T Homa, J Belin, A D Smith, J A Monro and K J Zilkha, Journal of Neurology, Neurosurgery and Psychiatry, vol 43, no 2, pp 106-110

'The Purification and Properties of Phospholipase A from Human Pancreas', W L Magee, J Gallai-Hatchard, H Sanders and RHST, Biochemical Journal, vol 83, pp 17-25

Wellcome uses cookies.

'The Purification and Properties of Phospholipase A from Human Pancreas', W L Magee, J Gallai-Hatchard, H Sanders and RHST, Biochemical Journal, vol 83, pp 17-25

Collection contents

About this work

Publication/Creation

Physical description

Permanent link