A hitherto unobserved effect of the salicylates / by G. A. Gibson and R. W. Felkin.

Date:
[1889?]
Catalogue details

Licence: Public Domain Mark

Credit: A hitherto unobserved effect of the salicylates / by G. A. Gibson and R. W. Felkin. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    A HITHERTO UNOBSERVED EFFECT OF THE SALICYLATES. BY G. A. GIBSON, M.D., D.SC., F.R.S.E., Lecturer on Materia Meclica, and Therapeutics in the Edinburgh Medical School, AND R. W. FELKIN, M.D., F.R.S.E., F.R.G.S., Ltdurcr on the Diseases of the Tropics and Climatology in the Edinburgh Medical School. Amongst the effects produced by the members of the salicy group upon the nervous system, mydriasis has been noticed iD association with the amblyopia frequently caused by the action of these drugs; but, so far as we know, myosis has not been observed as a result of their administration. In a case recently under our care extreme contraction of the pupil was caused by the use of large doses of salicylate of sodium, and as this symptom was somewhat misleading to us, we consider it our duty to make the facts known. The patient in this case was a lady of middle age, who fell ill on the evening of November 0. When she was first seen, early next morning, she complained of severe pains in the head and limbs, and tbe temperature was found to be 105 8° F., while the pulse was 104. In spite of the want of correspondence between the temperature and the pulse, it seemed probable that the condition was rheumatic in its nature, and the patient was ordered twenty grains of sodium salicylate every two hours. In the afternoon of the some day the pupils were found to be greatly contracted, and their reaction to light was absolutely lost, while the vision was distinctly impaired. Tinnitus aurium and deafness were also present, and were accompanied by severe Tuk Pbaxtitioxer.—Vol. xlii No. 1. C