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1. The Mechanism of Pain and its Bearing on the Diagnosis of Ulcer
2. The Pathogenesis of Ulcer, particularly with regard to the Role of Acid

Pickering, Sir George White

ARTICLES/PUBLICATIONS

Publications by GWP

Observations Upon Muscular Pain in Intermittent Claudication. Lewis, T., Pickering, G.W., and Rothschild, P. Heart, 1931, XV, No. 4, 359

Centripetal Paralysis Arising Out of Arrested Bloodflow to the Limb, including Notes on a Form of Tingling. Lewis, T., Pickering, G.W., and Rothschild, P. Heart, 1931, XVI, No. 1, 1.

Vasodilation in the Limbs in Response to Warming the Body: with Evidence for Sympathetic Vasodilator Nerves in Man. Lewis, T., and Pickering, G.W. Heart, 1931, XVI, No. 1, 33.

The Vasomotor Regulation of Heat Loss from the Human Skin in Relation to External Temperature. Heart, 1933, XVI, No. 2, 115

Headache Produced by Histamine and its Mechanism. Pickering, G.W., and Hess, W. BMJ, 1932, Dec 17, ii

Observations on the Mechanism of Headache Produced by Histamine. Clin. Sci., 1933, I, No. 1, 77

Vasodilation in the Hands and Feet in Response to Warming the Body. Clin. Sci., 1933, I, No. 2, 213

On the Clinical Recognition of Structural Disease of the Peripheral Vessels. BMJ, 1933, Dec 16, ii

Observations on Angina Pectoris and Intermittent Claudication in Anaemia. Pickering, G.W. and Wayne, E.J. Clin. Sci., 1934, I, No. 3, 305

Observations upon Maladies in which the Blood Supply to Digits ceases intermittently or permanently, and upon Bilateral Gangrene of Digits; Observations relevant to so-called "Raynaud's Disease". Lewis, T. and Pickering, G.W. Clin. Sci., 1934, I, No. 4, 327

Circulatory Changes in the Fingers in some Diseases of the Nervous System, with special reference to the Digital Atrophy of Peripheral Nerve Lesions. Lewis, T. and Pickering, G.W. Clin. Sci., 1936, 2, No. 2, 149

The Peripheral Resistance in Persistent Arterial Hypertension. Clin. Sci., 1936, 2, No. 2, 209

Observations on the Mechanism of Arterial Hypertension in Acute Nephritis. Clin. Sci., 1936, 2, No. 4, 363

Some Observations on Renin, a Pressor Substance Contained in Normal Kidney, together with a Method for its Biological Assay. Pickering, G.W. and Prinzmetal, M. Clin. Sci., 1938, 3, No. 2, 211

Acute Arterial Lesions in Rabbits with Experimental Renal Hypertension. Wilson, C. and Pickering, G.W. Clin. Sci., 1938, 3, No. 3, 343

Experimental Hypertension of Renal Origin in the Rabbit. Pickering, G.W. and Prinzmetal, M. Clin. Sci., 1938, 3, 357

The Problem of High Blood Pressure in Man. BMJ, 1939, i, 1

The Problem of High Blood Pressure in Man. J. Mt. Sinai Hosp, 1939, V, No. 6, 649

Experimental Observations on Headache. BMJ, 1939, i, 907

Hypertension Produced in the Rabbit by Prolonged Renin Infusion. Hill, J.R. and Pickering, G.W. Clin. Sci., 1939, 4, No. 2, 207

The Relationship of Benign and Malignant Hypertension. J. Mt. Sinai Hosp., 1942, VIII, No. 5, 916

The Assay of Renin in Rabbits with Experimental Renal Hypertension. Pickering, G.W., Prinzmetal, M., and Kelsall, A.R. Clin. Sci., 1942, 4, No. 4, 401

The Circulation in Arterial Hypertension. BMJ, 1943, ii, 1 and 31

The Role of the Kidney in Acute and Chronic Hypertension Following Renal Artery Constriction in the Rabbit. Clin. Sci., 1945, 5, Nos. 3 & 4, 229

Angina Pectoris and Tobacco. Pickering, G.W., and Sanderson, P.H. Clin. Sci., 1945, 5, Nos. 3 & 4, 275

In Memoriam. Sir Thomas Lewis. Clin. Sci., 1946, 6, Nos. 1 & 2, 3

Observations on the Mechanism of Pain in Ulcer of the Stomach and Duodenum. Pt. I - The Nature of the Stimulus. Bonney, G.L.W., and Pickering, G.W. Clin. Sci., 1946, 6, 63

Observations on the Mechanism of Pain in Ulcer of the Stomach and Duodenum. Pt. II - The Location of the Pain Nerve Endings. Bonney, G.L.W., and Pickering, G.W. Clin. Sci., 1946, 6, 91

Lumbar Puncture Headache. Brain, 1948, 71, pt. III, 274

The Aetiology of Constrictive Pericarditis, with special reference to Tuberculous Pericarditis, together with a note on Polyserositis. Andrews, G.W.S., Pickering, G.W., and Holmes Sellors, T. Quart. J. Med., 1948, 68, 291

Transient Cerebral Paralysis in Hypertension and in Cerebral Embolism. J.A.M.A., 1948, 137, 423

The Place of the Experimental Method in Medicine (President's Address -Section of Exper. Med. & Therapeutics). Proc. Roy. Soc. Med., 1949, XLII, No. 4, 229

The Teaching of Physiology. BMJ, 1949, ii, 502

The Role of Gastric Acidity in the Pathogenesis of Peptic Ulcer. James, A.H., and Pickering, G.W. Clin. Sci., 1949, 8, No. 3, 181

The Nature of the Action of Renin and Hypertension on Renal Function in the Rabbit. Hughes-Jones, N.C., Pickering, G.W., Sanderson, P.H., Scarborough, H., and Vandenbroucke, J. J. Physiol., 1949, 109, Nos. 3, & 4, 288

Hypertension Produced in the Rabbit by Long Continued Infusions of Renin. Blacket, R.B., Depoorter, A., Pickering, G.W., Sellers, A.L., and Wilson, G.M. Clin. Sci., 1950, 9, No. 2, 223

The Action of Noradrenaline in Man and its Relation to Phaeochromocytoma and Hypertension. Barnett, A.J., Blacket, R.B., Depoorter, A.E., Sanderson, P.H., and Wilson, G.M. Clin. Sci., 1950, 9, No. 2, 151

The Effects of Prolonged Infusions of Noradrenaline and Adrenaline on the Arterial Pressure of the Rabbit. Blacket, R.B., Pickering, G.W., and Wilson, G.M. Clin. Sci., 1950, 9, No. 2, 247

The Significance of the Discovery of the Effects of Cortisone on Rheumatoid Arthritis. Lancet, 1950, ii, 81

Peptic Ulcer. The Hume Lectures for 1950. Newcastle Med. J., 1951, XXIV, No. 3, 49

The Mechanism of Pain in Peptic Ulcer. Anatomy and Physiologyof upper gastro-intestinal tract 1951, Chapter 8. Edited D.J. Sandweiss, Saunders (Phila.)

Vascular Spasm. Lancet, 1951, ii, 845

Allergy and A.C.T.H. BMJ, 1952, i, 1207

The Natural History of Hypertension. Brit. Med. Bull., 1952, 8, No. 4, 305

The Production of Vascular Lesions and Cardiac Hypertrophy by Infusions of Renin and Noradrenaline in the Rabbit. Pugh, R.C.B., Pickering, G.W., and Blacket, R.B. Clin. Sci., 1952, II, No. 3, 241

The Pathogenesis of Malignant Hypertension. Circulation VI, 1952, No. 4, 599

Opportunity and the Universities. Lancet, 1952, ii, 895

The Reversibility of Malignant Hypertension. Pickering, G.W., Dickson Wright, A., and Heptinstall, R.H. Lancet, 1952, ii, 952

Blood Pressure - Treatment of Hypertension. Surgical Progress, 1952, p.151

Nephrectomy and other Treatment for Hypertension in Pyelonephritis. Pickering, G.W., and Heptinstall, R.H. Quart. J. Med., 1953, XVII, No. 85, 1

The Effects of Cortisone and Adrenocorticotrophic Hormone on Experimental Inflammations in the Human Skin. Lovell, R.R.H., Goodman, H.C., Hudson, B., Armitage, P. and Pickering, G.W. Clin. Sci., 1953, 12, No. 1, 41

The Aetiology of Essential Hypertension -1.The Arterial Pressure in the General Population. Hamilton, M., Pickering, G.W., Fraser Roberts, J.A., and Sowry, G.S.C. Clin. Sci., 1954, 13, No. 1, 11

The Aetiology of Essential Hypertension -2.Scores for Arterial Blood Pressures Adjusted for Differences in Ages and Sex. Hamilton, M., Pickering, G.W., Fraser Roberts, J.A., and Sowry, G.S.C. Clin. Sci., 1954, 13, No. 1, 37

The Aetiology of Essential Hypertension -3.The Effect of Correcting for Arm Circumference on the Growth Rate of Arterial Pressure with Age. Pickering, G.W., Fraser Roberts, J.A., and Sowry, G.S.C. Clin. Sci., 1954, 13, No. 2, 267

The Aetiology of Essential Hypertension 4.The Role of Inheritance. Hamilton, M., Pickering, G.W., Fraser Roberts, J.A., and Sowry, G.S.C. Clin. Sci., 1954, 13, No. 2, 273

Rene ed Ipertensione. Recenti Progressi in Medicina, Vol. XVI, No. 1 -Gennaio 1954

Meccanismo e valore diagnostico del dolore. Recenti Progressi in Medicina, Vol. XVII, No. 2 - Agosto 1954.

Reconstruction of Internal Carotid Artery in a Patient with Intermittent Attacks of Hemiplegia. Eastcott, H.H.G., Pickering, G.W., Rob, C.G. Lancet, 1954, Nov 13, pp.994-996

The Scientific Investigation of Therapeutic Action. Medicinsk Forum, No. 4, 1955, pp.97-110

Hypertonie und Niere. Klinische Wochenschrift, 1955, Apr 15, pp.370-372

The Genetic Factor in Essential Hypertension. Annals Int. Med., 1955, 43, No. 3, pp.457-464

Disorders of Contemporary Society and their Impact on Medicine, Lancet, 1955, pp.1149-1152

Disorders of Contemporary Society and their Impact on Medicine. Annals. Int. Med., 1955, 43, 5

The Concept of Essential Hypertension. Annals Int. Med., 1955, 43, No. 6, pp.1153-1160

Experimental Observations on Headache. Int. Arch. Allergy, 1955, 7, pp.279-284

The Role of the Genetic Factor in Hypertension. III Congress Int. Medicine

The Purpose of Medical Education. BMJ, 1956, ii, p.113 (July 21)

Controlled Trial of Effects of Cortisone Acetate in Status Asthmaticus. Lancet, 1956, pp.803-806

Natura e patogenesi dell'ipertensione essenziale. Recenti Progressi in Medicina, 1956, XXI, No. 5, pp.392-406

The Genetic Factor in Essential Hypertension. Acta Cardiologicai, Supplementum VI, 1956, pp.22-24

The Function of a Teaching Hospital. Lancet, 1957, pp.1-8

Treatment of Polyarteritis Nodosa with Cortisone: Results After one Year. BMJ, 1957, i, 608-611

The Genetic Component in High Blood Pressure. Triangle, 1957, III, No. 2, pp.59-66

Die Genetische Komponente bei der Hypertonie

Role du Facteur Genetique dans l'Hypertension.

Regulation of Body Temperature in Health and Disease. Lancet, 1958, Jan 4 & 11, pp.1-9, pp.59-64

Headache. Principles of Int. Med., 1958, 3, pp.18-28

The Location of Renin within the Kidney. J. Physiol 1958, 143, pp.78-79

A Rapid Method for Separating Glomeruli from Rabbit Kidney. Nature, 1958, 182, pp.1103-1104

Medicine's Challenge to the Educator. BMJ, 1958, ii, pp.1117-1121

The Influence of Vascular Changes in Progressive Failure of Vision. Trans. Ophthalmol Soc., 1958, LXXVIII, pp.295-301

Symposium on Cerebrovascular Disease Proc. Roy. Soc. Med., 1959, 52, No. 7, pp.540-542

Cardiovascular Diseases - Problems of Aetiology and Pathogenesis. Medical Surveys and Clinical Trials, 1959, 14, pp.238-260. (Ed. I.J. Witts)

The Quantitative Approach to Disease Exemplified by Essential Hypertension. Ciba Foundation Symposium on Significant Trends in Medical Research, 1959, pp.273-297

The Location of Renin in the Rabbit Kidney. Pickering, G.W., and Cook, W.F. J. Physiol., 1959, 149, pp.526-536

The Anatomical and Functional Aspects of the Neurological Lesions of Diabetes. Proc. Roy. Soc. Med., 1959, pp.142-143

A Study of Medical Education in Great Britain. J. Med. Ed., 1959, 34, No. 12, pp.1139-46

The Location of renin in the rabbit kidney. Cook, W.F., and Pickering, G.W. J. Physiol. (1959) 149, 526-536

The Location of Renin in the Rabbit Kidney. Cook, W.F. and Pickering, G.W. Polypeptides which Affect Smooth Muscles and Blood Vessels, 1960, pp.155-157

Starling and the Concept of Heart Failure. Circulation, 1960, XXI, No. 3, pp.324-331

The Nature of Essential Hypertension. Oldham, P.D., Pickering, G.W., Fraser Roberts, J.A., Sowry, G.S.C. Lancet, 1960, pp.1085-1093

Changes in the Fundus Oculi after Haemorrhage. Pears, M.A., and Pickering, G.W. Quarterly Journal of Medicine, Vol. XXIX, No. 114, April 1960

Clinical Problems and Results [lecture]

Inheritance of High Blood Pressure Reprint from Essential Hypertension, An International Symposium

Die Erblichkeit der Hypertonie

The Effects of Embolic Obstruction of Intrarenal Arteries in the Rabbit. Alexander, N., Heptinstall, R.H., and Pickering, G.W. Journal of Pathology and Bacteriology, Vol. 81, No. 1, pp.225-237, 1961

Fever and Pyrogens. The Scientific Basis of Medicine Annual Reviews

The Concept of Essential Hypertension as a Quantitative Disease (1961). Proc. of Prague Symposium, 1960. Proc. of Joint WHO/Czecho. Cardiological Society

Neuroretinopathy following Haemorrhage - Ashton, N, Pears, M.A., Pickering, G.W. British Journal of Ophthalmology, Vol. 45, No. 6, pp.385-394, June, 1961

Rapporti tra Fattori Genetici e Sociali e Pressione Arteriosa, Estratto da Recenti Progressi in Medicina, Vol. XXX, n.5, maggio, 1961

Language: The Lost Tool of Learning in Medicine and Science - Address given at the annual special meeting of the Middlesex Hospital Medical School, London, on May 11 1961 Lancet, 1961 i, 115

Postgraduate Medical Education: The Present Opportunity and the Immediate Need. BMJ, Feb 17, 1962. Vol. i, p.421-425

Headache - George Pickering. From "Pain": Principles of Internal Medicine, edited by T.R. Harrison et al. McGraw-Hill Book Co., Inc., 1962

The Nature of Transient Ischaemia of Brain and Retina. Arch. int. Pharmacodyn, CXL, No. 1-2

Arteriosclerosis and Atherosclerosis: The Need for clear thinking. American Journal of Medicine, Vol. 34, No. 1

Arterial Pressures of Relatives of Patients with Secondary and Malignant Hypertension. Hamilton, M., Pickering, G.W., Fraser Roberts, J.A., and Sowry, G.S.C. Clin. Sci. Vol 24, No. 1

Manners Makyth Man - A plea for the importance of character in Medicine. Presidential address to B.M.A. (1963). BMJ vol. ii, p.133, July 20th 1963

The Action of Angiotensin in Man. de Bono, E., de Lee, G., Mottram, R.F., Pickering, G.W., and Brown, J.J., Keen, H., Peart, W.S., and Sanderson, P.H. Clin. Sci., Vol. 25, No. 1, August 1963

Arterial occlusion especially of coronary arteries and of the subclavian and carotid arteries (Thayer Lectures I and II) Bulletin of the Johns Hopkins Hospital, Vol. 113 , No. 3 p.105-123, September 1963

The Future of the Medical Research Council. BMJ, (1963), ii, 1293, November 1963

Action of Renin and Angiotensin in the Renal Handling of Sodium and Chloride in Rabbits. Canadian Med. Ass. Journal, 90, 256, January 1964

Concluding Remarks - Symposium on Angiotensin, Montreal. Canadian Med. Ass. J., 90, 340

Pathogenesis of Myocardial and Cerebral Infarction: Nodular Arteriosclerosis (First Sir Thomas Lewis Lecture, delivered before British Cardiac Society, 25 Oct 1963). BMJ, 1964, i, 517

Mural Thrombosis of the Subclavian Artery and Subsequent Embolism in Cervical Rib. Gunning, A.J., Pickering, G.W., Robb-Smith, A.H.T., and Ross Russell, R. Q.J. Med., 1964, 33, 133

Mural Thrombosis of the Internal Carotid Artery and Subsequent Embolism. Gunning, A.J., Pickering, G.W., Robb-Smith, A.H.T., and Ross Russell, R. Q.J. Med., 1964, 33, 155

Arterial Occlusion: A Clinical and Experimental Study. Pointers and Pathways in Research, published by Ciba of India Ltd., Bombay

Variation in arterial pressure throughout the day and night. Richardson, D.W., Honour, A.J., Fenton, G.W., Stott, F.H., and Pickering, G.W. Clin. Sci., Vol 26, No 3, June 1964, p.445.

The location by regional cooling of central temperature receptors in the conscious rabbit. Downey, J.A., Mottram, R.F., and Pickering, G.W. J. Physiol. 1964, 170, 415-441.

Direction and prospects for research in geriatrics. Age with a Future, Munksgaard, Copenhagen

Physician and Scientist (Harveian Oration 1964). BMJ, 2, 1615-1619

The Universities and Society. The problem as seen from the oldest technology (Leeds Inaugural Lecture - 22 Oct 1964). Lancet, i, 57-61

The Action of Synethetic Angiotensin on Renal Function in the Unanaesthetized Rabbit. Langford, H.G., and Pickering, G.W. J. Physiol., 177, 161-173

The Purpose and Method of Medical Education. Israel Journal of Medical Sciences, 1, 3-6

Antihypertensive Drug Therapy - Another Appraisal. Pears, M.A., and Pickering, G.W. Arch. Intern. Med., 115, 526-528

Hypertension: Natural History, Diagnosis, Prognosis and Management. Medical Times, 93, 939

Heart Disease and Stroke. Medical Bulletin, University of Minnesota, Vol. 36, No. 10 June 1965

Assessment of Postgraduate Medical Education. A Report to the Nuffield Provincial Hospitals Trust. BMJ,, ii, 557-564

Hyperpiesis: High Blood-pressure without Evident Cause: Essential Hypertension (St. Cyres Lecture, 1964). BMJ, ii, 959-968 and 1021-1026

Planning a New Medical School (The Henry Simpson Newland Oration). Medical Journal of Australia, 2, 515

Education as an instrument of society. Harben Lectures 1965. Journal of the Royal Institute of Public Health and Hygiene

Cerebral vascular disease. Acta Medica Scandinavia, 1966, Suppl. 445.

A clinico-pathological study of aorta-iliac thrombosis (The Leriche Syndrome). Gunning, A.J., Hackett, M.E.J., Mackenzie, J.R., Oliver, D.O., Pickering, G.W., and Tibbs, D.J. Quart. J. Med., 1966, 35, 475

Essential hypertension. Das Medizinische Prisma No. 1, 1967 (Boehringer Ingelheim Ltd)

The production and resolution of hypertensive vascular lesions in the rabbit. Allison, P.R., Bleehan, N., Brown, W., Pickering, G.W., Robb-Smith, A.H.T., and Russell, R.P. Clin. Sci., 1967, 33, 39

Transplantation: The Medical, Ethical and Social Problems. New Scientist, 37, 122 (18th January 1968)

The relation of arterial pressure to sleep and arousal in man. Pickering, G.W., Sleight, P., and Smyth, H.S. J. Physiol. 1967, 191, 76p

The reflex regulation of arterial pressure during sleep in man. Pickering, G.W., Sleight, P., and Smyth, H.S. J. Physiol. 1968, 194, 46p

Diminished baroreflex sensitivity in high blood pressure. Bristow, J.D., Honour, A.J., Pickering, G.W., Sleight, P., and Smyth, H.S. Circulation, 1969, 39, 48

Reflex regulation of arterial pressure during sleep in man: A quantitative method of assessing baroreflex sensitivity. Smyth, H.S., Sleight, P., and Pickering, G.W. Circulation Res., 1969, 24, 109

Report by Sir George Pickering on visit to Romania from 22 to 30 September 1967. Royal Society O/16(68)

Peptic Ulcer. Proc. Roy. Aust. Coll. Phys., 1951, 6, 37 & 49

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Peptic Ulcer. Proc. Roy. Aust. Coll. Phys., 1951, 6, 37 & 49

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