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Edward's syndrome karyotype, 47,XY,+18

Wessex Reg. Genetics Centre

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Credit: Edward's syndrome karyotype, 47,XY,+18. Credit: Wessex Reg. Genetics Centre. Attribution 4.0 International (CC BY 4.0)

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Trisomy 18 syndrome (formerly Edward's syndrome) karyotype, 47,XY,+18 This human male has a normal chromosome complement, plus an extra chromosome 18. Symptoms include growth failure, mental retardation, hypertonicity, rocker-bottom flatfoot, flexion defomities of the fingers, and renal and cardiac anomalies. Sufferers seldom survive beyond six months. The syndrome is associated with advanced maternal age.

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