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Stories

  • Article

Deadly doses and the hardest of hard drugs

The invention of the modern hypodermic syringe meant we could get high – or accidentally die – faster than before. Find out how this medical breakthrough was adapted for deadly uses.

  • Article

The hell of hay fever

After years suffering in silence, David Jesudason finds speaking out about his pollen allergy gives him hope for a future where his hay-fever symptoms are under control.

  • Article

The rise and fall of a medical mesmerist

Uncover the fascinating story of the doctor who popularised hypnotism as a medical technique, and could name Dickens among his famous friends.

  • Book extract

Ayurveda: Knowledge for long life

The story of medicine in India is rich and complex. Aarathi Prasad investigates how it came to be this way.

All stories (6)

Images

  • Fellows of the Royal College of Physicians, Edinburgh. Photogravure by Barclay Bros., 1902.
  • Drugs and AIDS : 9.30 a.m. - 4.30 p.m. Wednesday, 17th May, 1989 : Royal College of Physicians, 9 Queen Street, Edinburgh, EH2 1JQ.
  • Drugs and AIDS : 9.30 a.m. - 4.30 p.m. Wednesday, 17th May, 1989 : Royal College of Physicians, 9 Queen Street, Edinburgh, EH2 1JQ.
  • Heads of fellows of the Royal College of Physicians of Edinburgh, around the programme for Scottish pipe music in honour of the International Ophthalmological Congress. Colour line block after George A. Fothergill, 1894.
  • The Addictions Forum in association with The Alcohol Research Group - the University of Edinburgh present the Third National Conference on Drugs & AIDS ... : 3 and 4 November 1992, Queen Mother Conference Centre, Royal College of Physicians, 9 Queen Street, Edinburgh EH12 1JQ.
  • A short account of cardiac murmurs : being a portion of a lecture on "Modern cardiac pathology and diagnosis" delivered before the Royal College of Physicians of Edinburgh / by W.T. Gairdner.
  • A short account of cardiac murmurs : being a portion of a lecture on "Modern cardiac pathology and diagnosis" delivered before the Royal College of Physicians of Edinburgh / by W.T. Gairdner.
  • Galega officinalis L. Fabaceae. Goat's Rue. Distribution: Central and Southern Europe, Asia Minor. Culpeper (1650) writes that it ‘... resists poison, kills worms, resists the falling sickness [epilepsy], resisteth the pestilence.’ Galega officinalis contains guanidine which reduces blood sugar by decreasing insulin resistance and inhibiting hepatic gluconeogenesis.. Metformin and Phenformin are drugs for type II diabetes that rely on this group of chemicals, known as biguanidines. Its name gala, meaning milk plus ega meaning 'to bring on', refers to its alleged property of increasing milk yield, and has been used in France to increase milk yield in cows. officinalis refers to its use in the offices of the monks, and is a common specific name for medicinal plants before 1600 and adopted by Linnaeus (1753). The fresh plant tastes of pea pods. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Veratrum nigrum L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and, when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying-in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum - and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Veratrum album L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum -and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
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Catalogue

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