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Coleridge’s hypochondria

An intense focus on his own bodily sensations led poet Samuel Taylor Coleridge to self-medicate with narcotics. But this fascination also put Coleridge ahead of the medical sensibilities of his day.

  • Article

Drug sharing in desperate times

When Nicole was threatened with deportation, her mental health deteriorated. Now without a job, a passport or a doctor, she depends on others to send her their leftover anxiety drugs.

  • Article

The mystery of the malignant brain

In 1884 a neurologist successfully used a patient’s symptoms, plus a new kind of map, to locate a brain tumour. Discover how his best-laid plans for treatment worked out.

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Images

  • Trypanosomiasis diagnosis laboratory, Uganda
  • Papanicolaou stained smear of a clival chordoma, microscopy. Chordomas are cancers formed of cells which resemble those of the notochord (spine) of a developing foetus. Although they can present anywhere within the spine and skull, the majority grow in the sacral region of the spine, corresponding to the lower back. This image shows a Papanicolaou (Pap) stained smear obtained from a needle biopsy of a chordoma in the clivus, a part of the cranium at the base of the skull.
  • Papanicolaou stained smear of a C2 vertebral chordomal mass, microscopy. Chordomas are cancers formed of cells which resemble those of the notochord (spine) of a developing foetus. Although they can present anywhere within the spine and skull, the majority grow in the sacral region of the spine, corresponding to the lower back. This image shows a Papanicolaou (pap) stained smear obtained from a needle biopsy of a chordoma of the C2 vertebrae, located at the top of the neck just underneath the base of the skull.
  • MGG stained smear of a C2 vertebral chordomal mass
  • Squamous carcinoma of lacrimal gland, microscopy
  • Multinucleated giant cell containing an asteroid, microscopy.
  • Section of a cystic mass isolated from the parotid gland
  • Myxoid liposarcoma, microscopy
  • Calcium oxalate crystals in urinary sediment
  • Metastatic seminoma of supraclavicular lymph node
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