408 results filtered with: Poison
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Pulsatilla vulgaris Mill. Ranunculaceae. Pasque flower. Distribution: Europe. Lindley (1838) and Woodville (1790) knew this as Anemone pulsatilla, the common name being Pasque (Easter) Flower. At the end of the 18th century it was recommended for blindness, cataracts, syphilis, strokes and much more, treatments which, as was clear to physicians at the time, were valueless. Gerard (1633) writes: ‘They serve only for the adorning of gardens and garlands, being floures of great beauty’. It is in the buttercup family, Ranunculaceae, all members of which are poisonous. It was recommended, by mouth, for ‘obstinate case of taenia’ (tapeworms). One hopes it was more toxic to the worm than the patient. Flowers with a central disc and radiating florets were regarded as being good for eye complaints under the Doctrine of Signatures. Porta (1588) writes (translated): ‘Argemone [Papaver argemone], and anemone, have flowers of this shape, from this they cure ulcers and cloudiness of the cornea’. There were occupational diseases even before there were words like pneumoconiosis, and Lindley writes that ‘the powder of the root causes itching of the eyes, colic and vomiting, if in pulverising it the operator do not avoid the fine dust which is driven up.’ Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Papaver somniferum L. Papaveraceae Opium Poppy Distribution: Asia minor, but has been dated to 5000BC in Spanish caves. Now grows almost everywhere. The oldest medicine in continuous use, described in the Ebers' papyrus (1550 BC), called Meconium, Laudanum, Paregoric and syrup of poppies. Culpeper (1650) on Meconium '...the juyce of English Poppies boyled till it be thick' and 'I am of the opinion that Opium is nothing else but the juyce of poppies growing in hotter countries, for such Opium as Authors talk of comes from Utopia.[he means an imaginary land, I suspect]’]. He cautions 'Syrups of Poppies provoke sleep, but in that I desire they may be used with a great deal of caution and wariness...' and warns in particular about giving syrup of poppies to children to get them to sleep. The alkaloids in the sap include: Morphine 12% - affects ?-opioid receptors in the brain and causes happiness, sleepiness, pain relief, suppresses cough and causes constipation. Codeine 3% – mild opiate actions – converted to morphine in the body. Papaverine, relaxes smooth muscle spasm in arteries of heart and brain, and also for intestinal spasm, migraine and erectile dysfunction. Not analgesic. Thebaine mildly analgesic, stimulatory, is made into oxycodone and oxymorphone which are analgesics, and naloxone for treatment of opiate overdose – ?-opioid receptor competitive antagonist – it displaces morphine from ?-opioid receptors, and constipation caused by opiates. Protopine – analgesic, antihistamine so relieves pain of inflammation. Noscapine – anti-tussive (anti-cough). In 2006 the world production of opium was 6,610 metric tons, in 1906 it was over 30,000 tons when 25% of Chinese males were regular users. The Opium wars of the end of the 19th century were caused by Britain selling huge quantities of Opium to China to restore the balance of payments deficit. Laudanum: 10mg of morphine (as opium) per ml. Paregoric: camphorated opium tincture. 0.4mg morphine per ml. Gee’s Linctus: up to 60 mg in a bottle. J Collis Browne’s chlorodyne: cannabis, morphine, alcohol etc. Kaolin and Morph. - up to 60 mg in a bottle. Dover’s Powders – contained Ipecacuana and morphine. Heroin is made from morphine, but converted back into morphine in the body (Oakeley, 2012). One gram of poppy seeds contains 0.250mgm of morphine, and while one poppy seed bagel will make a urine test positive for morphine for a week, one would need 30-40 bagels to have any discernible effect. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Watsonia pillansii L.Bolus Iridaceae Bugle lily, Distribution: South Africa. Named for Sir William Watson (1715-1787), British botanist and physician, sometime censor at the Royal College of Physicians, London. No medicinal uses. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Scutellaria baicalensis Georgi Lamiaceae. Baikal skullcap. Distribution: China. There are several hundred species of Scutellaria, also known as skull caps, so correct identification is important - in particular from Scutellaria lateriflora an American species known as Blue skullcap. The latter is used as an abortifacient and to expel placenta by the Cherokee and for cleaning the throat by the Iroquois (Austin, 2004). Much vaunted as a treatment for rabies with unlikely statistics (1,400 cases cured by one doctor alone). Also as ‘antispasmodic, nervine, [for] chorea, convulsions, tetanus, tremors, delirium tremens, [and as a] diaphoretic and diuretic'. Toxicity symptoms include mental confusion, stupor, headache, vertigo, photophobia, dilated pupils, difficulty in micturition, bradycardia, tremulousness and languor, followed by wakefulness and restlessness (Milspaugh, 1974). Hutchens (1991) reported that it reduces sexual desire and was used for almost every nervous illness. Scutellaria baicalensis contains baicalin, baicalein and wogonin (European Medicines Agency, September 2010). It is used in Traditional Chinese Medicine for treating inflammation, cancer, bacterial and viral infections of the lungs and gut and is one of the '50 Chinese herbs' in the lists of some authors. Scutellaria lateriflora (combined with Verbena officinalis, Passiflora incarnata and the seed of Avena sativa (oats) is licensed for use in Britain as a herbal medicine for temporary relief of mild symptoms of stress such as mild anxiety and to aid sleep, based upon traditional use only. Scutellaria baicalensis is not licensed for use in the UK (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Papaver rhoeas L. Papaveraceae Corn Poppy, Flanders Poppy. Distribution: Temperate Old World. Dioscorides (Gunther, 1959) recommended five or six seed heads in wine to get a good night's sleep the leaves and seeds applied as a poultice to heal inflammation, and the decoction sprinkled on was soporiferous. Culpeper (1650) ' ... Syrup of Red, or Erratick Poppies: by many called Corn-Roses. ... Some are of the opinion that these Poppies are the coldest of all other - believe them that list [wishes to]: I know no danger in this syrup, so it be taken in moderation and bread immoderately taken hurts
Dr Henry Oakeley
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Fargesia rufa T.P.Yi Poaceae. Farges bamboo. Distribution: China. Named, in 1985, after Paul Guillaume Farges (1844-1912), a French missionary and plant collector, who went in 1867 with the Missions Étrangères to north-east Szechuan. He botanised extensively and amassed 4,000 herbarium specimens which he sent back o France. He discovered and sent back seeds of the handkerchief tree, Davidia involucrata, one of which germinated after 18 months. Eighty plants have been named after him. (Cox, 1945
Dr Henry Oakeley
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Paeonia suffruticosa 'Chang Zhi Hong'
Dr Henry Oakeley
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Cup of Rhinoceros Horn
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Ribes odoratum H.L.Wendl Grossulariaceae Buffalo currant. Distribution: North America. Fruits edible. Presumably a source of vitamin C but no medicinal use. No reports of medicinal usage by Native Americans found. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Camassia leichtlinii (Baker)S.Watson Hyacinthaceae. Great Camas, Quamash. The species was named for Maximillian Leichtlin (1831-1910 of Baden , Germany, bulb enthusiast who corresponded with J.G. Baker at Kew. Bulbous herb. Distribution: North America. The bulbs of Camassia species were eaten by the Native Americans, the Nez Perce, after cooking by steaming for a day - which suggests they may be poisonous raw. They gave them to the American explorers, Meriwether Lewis and William Clerk, on their expedition (1804-1806) when they ran out of food. The bulbs of the similar looking 'Death camus', Toxicoscordion venenosum have been fatal when ingested by mistake (RBG Kew on-line). Steroidal saponins, which are precursors in the manufacture of steroids and cytotoxic activity has been detected in the sap of the bulbs. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Onychium japonicum 'Dali'
Dr Henry Oakeley
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Echinacea purpurea (L.) Moench Asteraceae. Coneflower. Distribution: North America. Austin (2004) records that the roots were chewed, or used as a tincture for coughs by the Choctaw. Combined with Rhus typhina to treat venereal disease by the Delaware. Very little record of this being used by Native Americans, who used E. angustifolia very widely - Regarded as a panacea and magical herb. This and E. pallida were used to treat snakebite, spider bite, cancer, toothache, burns, sores, wounds, flu and colds. E. purpurea in modern times has been used as an ‘immunostimulant’, but is known to cause a fall in white cell count, and to be purely a placebo. Licensed for use as a Traditional Herbal Medicine, which does not require proof of efficacy, in the UK. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Tragopogon pratensis L. Asteraceae Goats beard, Salsify, Jack-go-to-bed-at-noon. Distribution: Europe and North America. This is the Tragopogion luteum or Yellow Goats-beard of Gerard (1633) who recommended them boiled until tender and then buttered as being more delicious than carrots and parsnips and very nutritious for those sick from a long lingering disease. Boiled in wine they were a cure for a 'stitch' in the side. In the USA children collect the milky sap onto a piece of glass and, when dry, chew it as bubble-gum. The name 'Jack-go-to-bed-at-noon' referes to the flowers which close at noon and the spherical radiation of seed plumules which then appear. Salsify is now applied as a name for T. porrifolius and Scorzonera hispanica. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Zantedeschia aethiopica (L)Spreng. Calla lily, Arum lily. Half hardy annual. Distribution: South Africa. The genus name commemorates Giovanni Zantedeschi (1773-1846) an Italian physician and botanist. Born in Molina he studied medicine in Verona and Padua. He corresponded with the German botanist, Kurt Sprengel, who named the genus Zantedeschia in his honour in 1826, separating it from Calla, where, as C. aethiopica, it had been previously described by Linnaeus. He had broad interests, including the effect of different parts of the spectrum of light on plant growth, reporting in 1843, that red, orange and yellow light are heliotropically inactive. The botanic museum in Molina is dedicated to his memory. Aethiopica, merely means 'African'. The leaves are used as a warm poultice for headaches in ‘muthi’ medicine. It has become an invasive weed in parts of Australia. It was introduced, as a greenhouse plant, to Europe in the mid-17th century, where the long lasting flowers are popular in flower arranging and for weddings and funerals – a curious combination (Oakeley, 2012). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Polygala myrtifolia 'Grandiflora'
Dr Henry Oakeley
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Galega officinalis L. Fabaceae. Goat's Rue. Distribution: Central and Southern Europe, Asia Minor. Culpeper (1650) writes that it ‘... resists poison, kills worms, resists the falling sickness [epilepsy], resisteth the pestilence.’ Galega officinalis contains guanidine which reduces blood sugar by decreasing insulin resistance and inhibiting hepatic gluconeogenesis.. Metformin and Phenformin are drugs for type II diabetes that rely on this group of chemicals, known as biguanidines. Its name gala, meaning milk plus ega meaning 'to bring on', refers to its alleged property of increasing milk yield, and has been used in France to increase milk yield in cows. officinalis refers to its use in the offices of the monks, and is a common specific name for medicinal plants before 1600 and adopted by Linnaeus (1753). The fresh plant tastes of pea pods. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Trifolium rubens L. Leguminosae. [Note the Family Leguminosae is preferred over Family Fabaceae as the former allows all the legumes to be in one Family and not three - one Family being the current consensus among botanists]. Red Feather Clover. Distribution: Europe. The white clover, Trifolium repens, is listed as a treatment for arthritis by Linnaeus (1782). This and Trifolium pratense, Red Clover, are the ones most used for pastures. All the clovers have root nodules which fix nitrogen from the air into the soil so have an important role in ensuring soil fertility. Trifolium rubens has the same nitrogen fixing ability, and is used as an ornamental garden plant where it still acts to improve fertility. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Erythrina crista-galli L. Fabaceae. Cockspur coral tree. Distribution: South America. The national tree of Argentina, its flowers are pollinated by perching birds unlike many other species which are pollinated by humming birds. An extract from the bark is used as a powerful soporific, also as a gargle for sore throats and in the treatment of cuts, rheumatism and hepatitis, in Brazil (Mors, 1998). The seed contains the alkaloid beta-erythroidine. Analgesics, antimicrobial and anti inflammatory substances are being sought from the leaves. Curare-like action in rats has been reported from the seeds. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Rosa damascena Mill. Rosaceae Distribution: Garden origin. A hybrid between R. gallica and R. moschata.. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Veronicastrum virginicum 'Pink Glow'
Dr Henry Oakeley
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Xanthorhiza simplicissima Marshall Ranunculaceae. Yellow root. Distribution: North America, where it was discovered by the plant collector and explorer William Bartram in 1773. Yellow-root. Austin (2004) reports that of the Native Americans, the Cherokee use the crushed plant to make a yellow dye
Dr Henry Oakeley
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Physocarpus opulifolius (L.)Maxim. Roasaceae Distribution: North America. Austin (2004) reported it was used for gynaecological problems by the Iroquois and Menomini
Dr Henry Oakeley
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Neottia ovata plus Cantharis rufipes beetle
Dr Henry Oakeley
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Protea cyanoides L. Proteaceae King Protea Distribution
Dr Henry Oakeley
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Viburnum japonicum Spreng. Caprifoliaceae Evergreen Shrub. Distribution: Japan and Taiwan. No medicinal uses. The fruit is a 'famine food' eaten when all else fails. As other seeds/fruits of Viburnum species are listed as poisonous, and none are listed as 'edible', one can assume that the seeds/fruits of V. japonicum are also toxic. It does not appear vulnerable to pests or molluscs which may be due to irioid glycosides that are present in this genus produced as a defence against herbivores, fungi and bacteria. They have a bitter taste. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley