A depressed scholar surrounded by mythological figures; representing the melancholy temperament. Etching by J.D. Nessenthaler, ca. 1750.

A physician advising a man not to be depressed by his illness. Wood engraving after G. Du Maurier.

A man suffering from depressed spirits ("hypochondria"), being tormented by doleful spectres. Coloured etching by T. Rowlandson after J. Dunthorne, 1788.

A man suffering from depressed spirits ("hypochondria") being tormented by doleful spectres. Coloured etching by T. Rowlandson after J. Dunthorne, 1788.

A depressive man standing by a country pond in the pouring rain - not helping his state of mind. Wood engraving, 1869.

Right profile of head with depressed frontal lobes, divided up to show the location of all the lobes. Drawing, c. 1900.

A poor depressed man prepares to hang himself in a noose attached to the ceiling. Etching by T.L. Busby, ca. 1826.

Japanese Vigor Tonic : the best and safest for restoring the system after depressing or wasting diseases, or at any time when it has become impaired through over-work, mental anxiety or excess / J.H. Hart.

Anafranil : the international antidepressant.

Geigy : Tofranil Thymoleptic.

The anatomy of melancholy : what it is, with all the kinds causes, symptomes, prognostickes, & seuerall cures of it in three partitions, with their severall sections, members & subsections, philosophically, medicinally, historically, opened & cut up / By Democritus Junior [pseud.] With a satyricall preface, conducing to the following discourse.

The anatomy of melancholy : what it is with all the kinds, causes, symptons, prognostics & several cures of it / In three partitions with their several sections members & subsections philosophically, medicinally, historically opened & cut up by Democritus Junior [Robert Burton] with a satirical preface conducing to the following discourse.

Appetite control / Messrs Mayrs Agencies ; Clinical Products Ltd.

Étude sur la mélancolie / [Paul Ferdinand Gachet].

News : inexpensive sustained dexamphetamine therapy 'for the patient who is tired all day', 'for day-long appetite control' : dexten ion-resin-bonded dexamphetamine, barbidex dexten plus phenobarbitone / Clinical Products Ltd.

CPL pharmaceutical preparations / Clinical Products Ltd.

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