Developing muscles and their innervation during metamorphosis

"H. & E." exercise course : a three months' course of physical exercises for developing those muscles which have a vital bearing upon the general health / Health Promotion, Ltd., 19-21 Ludgate Hill, London, E.C.4.

Veratrum nigrum L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and, when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying-in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum - and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.

Veratrum album L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum -and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.

La Culture Physique, 1904, Max Unger.

Splendid physical types shown here are illustrative of some of the results that followed Eugene Sandow's lecture tour

From all over the world... : they keep writing in to say: Dear Mr. Atlas ... "look what you have done for ME" / Charles Atlas.

Types os superb physical manhood who have been developed to this high degree of physical fitness and resistant power to disease by the very methods I am advocating in this book, and have been advocating consistently all over the world for the past quarter of a century. This is the type of youthfull manhood that we could and should have had if my advice had been taken and followed, as recruits, instead of such weedy specimens of humanity as shown in the previous picture.

The first photo shows the physical condition of the youth of the nation as revealed by the war. The second shows what can be achieved by scientific methods of physical education and culture, and how imperative such methods are to safeguard us against physical deterioration and disease in future years.

Don't waste your time or money on ROT! : Here's what I'm ready to do: I'll prove in just 7 days YOU can have a body like mine / Charles Atlas.

Analysis and enrolment form for the attention of Charles Atlas : 40-42, Chandos Street, London, W.CA.

Somites in the chick embryo

Zebrafish embryos with green fluorescent myotomes

Cadbury's Cocoa : absolutely pure / Cadbury's.

Virile manhood : the official organ of the Laurance Institute of Health & Stamina Ltd. / Harold Laurance.

The Sandell-Gray Figure Trainer : a revolution in physical appliances ... / Sandell-Gray Figure Trainer Ltd.

Embryonic mouse limb

Poly-innervated neuromuscular junctions

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