Wellcome uses cookies.

Read our policy
Wellcome Collection homepage
All
Stories
Images
Catalogue
Events
43 results
  • James Johnson. Lithograph by T. Brigford.
  • Charles Robert Darwin. Wood engraving by T. Johnson, 1883, after L. Darwin, 1874.
  • Charles Robert Darwin. Wood engraving by T. Johnson, 1883, after L. Darwin, 1874.
  • Sir John Frederick William Herschel. Wood engraving by T. Johnson after Julia Margaret Cameron, 1867.
  • The sportsman's cyclopaedia; comprising a complete elucidation of the science and practice of hunting, shooting, coursing, racing, fishing, hawking, cockfighting, and other sports and pastimes of Great Britain, interspersed with entertaining and illustrative anecdotes / by T.B. Johnson.
  • The sportsman's cyclopaedia; comprising a complete elucidation of the science and practice of hunting, shooting, coursing, racing, fishing, hawking, cockfighting, and other sports and pastimes of Great Britain, interspersed with entertaining and illustrative anecdotes / by T.B. Johnson.
  • Taxus baccata L. Taxaceae European Yew. Trees are feminine in Latin, so while Taxus has a masculine ending (-us), its specific name, baccata (meaning 'having fleshy berries' (Stearn, 1994)), agrees with it in gender by having a female ending ( -a). Distribution: Europe. Although regarded as poisonous since Theophrastus, Gerard and his school friends used to eat the red berries (they are technically called 'arils') without harm. Johnson clearly ate the fleshy arils and spat out the seed, which is as poisonous as the leaves. It is a source of taxol, an important chemotherapeutic agent for breast and other cancers. It was first extracted from the bark of T. brevifolia, the Pacific yew tree, in 1966. About 1,100 kg of bark produces 10 g of taxol, and 360,000 trees a year would have been required for the needs of the USA – an unsustainable amount. In 1990 a precursor of taxol was extracted from the needles of the European yew so saving the Pacific trees. It is now produced in fermentation tanks from cell cultures of Taxus. Curiously, there is a fungus, Nodulisporium sylviforme, which lives on the yew tree, that also produces taxol. Because taxol stops cell division, it is also used in the stents that are inserted to keep coronary arteries open. Here it inhibits – in a different way, but like anti-fouling paint on the bottom of ships – the overgrowth of endothelial cells that would otherwise eventually block the tube. The economic costs of anticancer drugs are significant. Paclitaxel ‘Taxol’ for breast cancer costs (2012) £246 every 3 weeks
  • The connexion of life with respiration; or, an experimental inquiry into the effects of submersion, strangulation, and several kinds of noxious airs, on living animals: with an account of the nature of the disease they produce; its distinction from death itself; and the most effectual means of cure / By Edmund Goodwyn.
  • The history and present state of electricity, with original experiments / By Joseph Priestley.
  • The history and present state of electricity, with original experiments / By Joseph Priestley.
  • The history and present state of electricity, with original experiments / By Joseph Priestley.
  • A treatise on the cow-pox; containing the history of vaccine inoculation, and an account of the various publications which have appeared on that subject. In Great Britain, and other parts of the world / by John Ring.
  • A treatise on the cow-pox; containing the history of vaccine inoculation, and an account of the various publications which have appeared on that subject. In Great Britain, and other parts of the world / by John Ring.
  • A treatise on the cow-pox; containing the history of vaccine inoculation, and an account of the various publications which have appeared on that subject. In Great Britain, and other parts of the world / by John Ring.
  • A treatise on the cow-pox; containing the history of vaccine inoculation, and an account of the various publications which have appeared on that subject. In Great Britain, and other parts of the world / by John Ring.
  • A Ground Plan of the Magdalen Hospital in St. George's Fields.
  • Dissertatio medica inauguralis de quassia et lichene Islandico / [J.D.P.C. Ebeling].
  • Dissertatio medica inauguralis de quassia et lichene Islandico / [J.D.P.C. Ebeling].
  • The entire works of Dr Thomas Sydenham : newly made English from the originals: wherein the history of acute and chronic diseases, and the safest and most effectual methods of treating them, are faithfully, clearly, and accurately delievered. To which are added, explanatory and practical notes, from the best medicinal writers.
  • Tunbridge Wells, Kent: visitors to the wells and characters of the town in August 1748. Etching after T. Loggon, 1804.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.
  • The entire works of Dr. Thomas Sydenham, newly made English from the originals: wherein the history of acute and chronic diseases, and the safest and most effectual methods of treating them, are faithfully, clearly, and accurately delivered. To which are added, explanatory and practical notes, from the best medicinal writers / By John Swan.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.
  • Experiments and observations on different kinds of air, and other branches of natural philosophy, connected with the subject ... / being the former six volumes abridged and methodized, with many additions. By Joseph Priestley.