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37 results
  • HIV proteinase with inhibitor
  • Molecular model of renin inhibitor
  • Molecular model of renin inhibitor
  • Ribonuclease A with bound inhibitor
  • Molecular model of renin-inhibitor complex
  • Molecular model of renin-inhibitor complex
  • Molecular model of renin-inhibitor complex
  • Angiogenin - Placental ribonuclease inhibitor complex
  • AIDS, HIV proteinase with inhibitor, m.model
  • AIDS, HIV proteinase with inhibitor, m.model
  • Antistin-Privine relieves nasal congestion : for routine cough control Tessalon Perles : selective inhibitor of the cough reflex.
  • Antistin-Privine relieves nasal congestion : for routine cough control Tessalon Perles : selective inhibitor of the cough reflex.
  • Molecular models of renin inhibitors
  • Galanthus nivalis L. Amaryllidaceae Snowdrop. Hardy, bulbous herb. Distribution: Europe. A chemical, galantamine, is sourced principally from the Caucasian snowdrop, Galanthus woronowii but is present in our ‘English’ snowdrop and related genera. It is a competitive, reversible, acetylcholinesterase inhibitor so increases brain acetylcholine, a chemical of great importance in cerebral function. As such it has been recommended for ameliorating the symptoms of mild to moderate Alzheimer’s disease, but not for mild cognitive impairment as in US clinical trials there was an increased mortality. Johnson (Gerard, 1633) calls it the bulbous violet, Viola theophrasti
  • Veratrum nigrum L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and, when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying-in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum - and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Veratrum album L. Melanthiaceae Distribution: Europe. Cows do not eat Veratrum species in the meadows, and human poisoning with it caused vomiting and fainting. In the 1850s it was found to reduce the heart's action and slow the pulse (Bentley, 1861, called it an 'arterial sedative'), and in 1859 it was used orally in a woman who was having convulsions due to eclampsia. Dr Paul DeLacy Baker in Alabama treated her with drops of a tincture of V. viride. She recovered. It was used thereafter, as the first choice of treatment, and when blood pressure monitoring became possible, it was discovered that it worked by reducing the high blood pressure that occurs in eclampsia. By 1947 death rates were reduced from 30% to 5% by its use at the Boston Lying in Hospital. It works by dilating the arteries in muscles and in the gastrointestinal circulation. A further use of Veratrum species came to light when it was noted that V. californicum -and other species - if eaten by sheep resulted in foetal malformations, in particular only having one eye. The chemical in the plant that was responsible, cyclopamine, was found to act on certain genetic pathways responsible for stem cell division in the regulation of the development of bilateral symmetry in the embryo/foetus. Synthetic analogues have been developed which act on what have come to be called the 'hedgehog signalling pathways' in stem cell division, and these 'Hedgehog inhibitors' are being introduced into medicine for the treatment of various cancers like chondrosarcoma, myelofibrosis, and advanced basal cell carcinoma. The drugs are saridegib, erismodegib and vismodegib. All the early herbals report on its ability to cause vomiting. As a herbal medicine it is Prescription Only, via a registered dentist or physician (UK Medicines and Healthcare Products Regulatory Agency (MHRA)). Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • AIDS, reverse transcriptase/Hept complex
  • AIDS, reverse transcriptase/Hept complex
  • AIDS, reverse transcriptase/Nev complex
  • AIDS, reverse transcriptase/Nev complex
  • Reduction in mRNA levels due to RNAi
  • Spinal cord showing presence of siRNA
  • Inhibition of CDK2 by staurosporine, model
  • Cocaine crystals
  • Action of SSRIs and NRIs
  • Action of SSRIs and NRIs
  • Action of SSRIs and NRIs
  • AIDS, HIV proteinase, molecular model
  • AIDS, HIV proteinase, molecular model
  • Complex of RalA and C3bot proteins