Growing up with bananas / Tesco.

Sallot (?) holding up a tooth and leaning on a grossly oversized set of dentures through which a fleur-de-lis is growing, in the background is a oversized skull wearing a helmet. Coloured wood engraving (?) by Marchandeux after A. Gill, 1867.

"Mama, shall I have beautiful long hair like you when I grow up?" : "Certainly my dear, if you use 'Edwards' Harlene'." / Edwards' Harlene Co.

Papaver somniferum L. Papaveraceae Opium Poppy Distribution: Asia minor, but has been dated to 5000BC in Spanish caves. Now grows almost everywhere. The oldest medicine in continuous use, described in the Ebers' papyrus (1550 BC), called Meconium, Laudanum, Paregoric and syrup of poppies. Culpeper (1650) on Meconium '...the juyce of English Poppies boyled till it be thick' and 'I am of the opinion that Opium is nothing else but the juyce of poppies growing in hotter countries, for such Opium as Authors talk of comes from Utopia.[he means an imaginary land, I suspect]’]. He cautions 'Syrups of Poppies provoke sleep, but in that I desire they may be used with a great deal of caution and wariness...' and warns in particular about giving syrup of poppies to children to get them to sleep. The alkaloids in the sap include: Morphine 12% - affects ?-opioid receptors in the brain and causes happiness, sleepiness, pain relief, suppresses cough and causes constipation. Codeine 3% – mild opiate actions – converted to morphine in the body. Papaverine, relaxes smooth muscle spasm in arteries of heart and brain, and also for intestinal spasm, migraine and erectile dysfunction. Not analgesic. Thebaine mildly analgesic, stimulatory, is made into oxycodone and oxymorphone which are analgesics, and naloxone for treatment of opiate overdose – ?-opioid receptor competitive antagonist – it displaces morphine from ?-opioid receptors, and constipation caused by opiates. Protopine – analgesic, antihistamine so relieves pain of inflammation. Noscapine – anti-tussive (anti-cough). In 2006 the world production of opium was 6,610 metric tons, in 1906 it was over 30,000 tons when 25% of Chinese males were regular users. The Opium wars of the end of the 19th century were caused by Britain selling huge quantities of Opium to China to restore the balance of payments deficit. Laudanum: 10mg of morphine (as opium) per ml. Paregoric: camphorated opium tincture. 0.4mg morphine per ml. Gee’s Linctus: up to 60 mg in a bottle. J Collis Browne’s chlorodyne: cannabis, morphine, alcohol etc. Kaolin and Morph. - up to 60 mg in a bottle. Dover’s Powders – contained Ipecacuana and morphine. Heroin is made from morphine, but converted back into morphine in the body (Oakeley, 2012). One gram of poppy seeds contains 0.250mgm of morphine, and while one poppy seed bagel will make a urine test positive for morphine for a week, one would need 30-40 bagels to have any discernible effect. Photographed in the Medicinal Garden of the Royal College of Physicians, London.

Papaver somniferum L. Papaveraceae Opium Poppy Distribution: Asia minor, but has been dated to 5000BC in Spanish caves. Now grows almost everywhere. The oldest medicine in continuous use, described in the Ebers' papyrus (1550 BC), called Meconium, Laudanum, Paregoric and syrup of poppies. Culpeper (1650) on Meconium '...the juyce of English Poppies boyled till it be thick' and 'I am of the opinion that Opium is nothing else but the juyce of poppies growing in hotter countries, for such Opium as Authors talk of comes from Utopia [he means an imaginary land, I suspect]’. He cautions 'Syrups of Poppies provoke sleep, but in that I desire they may be used with a great deal of caution and wariness...' and warns in particular about giving syrup of poppies to children to get them to sleep. The alkaloids in the sap include: Morphine 12% - affects ?-opioid receptors in the brain and causes happiness, sleepiness, pain relief, suppresses cough and causes constipation. Codeine 3% – mild opiate actions – converted to morphine in the body. Papaverine, relaxes smooth muscle spasm in arteries of heart and brain, and also for intestinal spasm, migraine and erectile dysfunction. Not analgesic. Thebaine mildly analgesic, stimulatory, is made into oxycodone and oxymorphone which are analgesics, and naloxone for treatment of opiate overdose – ?-opioid receptor competitive antagonist – it displaces morphine from ?-opioid receptors, and reverses the constipation caused by opiates. Protopine – analgesic, antihistamine so relieves pain of inflammation. Noscapine – anti-tussive (anti-cough). In 2006 the world production of opium was 6,610 metric tons, in 1906 it was over 30,000 tons when 25% of Chinese males were regular users. The Opium wars of the end of the 19th century were caused by Britain selling huge quantities of Opium to China to restore the balance of payments deficit. Laudanum: 10mg of morphine (as opium) per ml. Paregoric: camphorated opium tincture. 0.4mg morphine per ml. Gee’s Linctus: up to 60 mg in a bottle. J Collis Browne’s chlorodyne: cannabis, morphine, alcohol etc. Kaolin and Morph. - up to 60 mg in a bottle. Dover’s Powders – contained Ipecacuana and morphine. Heroin is made from morphine, but converted back into morphine in the body (Oakeley, 2012). One gram of poppy seeds contains 0.250mgm of morphine, and while one poppy seed bagel will make a urine test positive for morphine for a week, one would need 30-40 bagels to have any discernible effect. Photographed in the Medicinal Garden of the Royal College of Physicians, London.

Blagraves astrological practice of physick discovering the true way to cure all kinds of diseases ... being performed by such herbs and plants which grow within our own nation, directing the way to distil and extract their vertues and making up of medicines. Also a discovery of some notable phylosophical secrets ... relating to a discovery of all kinds of evils, whether natural, or such which come from sorcery or witchcraft ... directing how to cast forth the said evil spirit out of any one which is possessed with sundry examples thereof / [Joseph Blagrave].

Cistus incanus ssp creticus Juss. Cistaceae. Rock Rose. Distribution: Crete. Interesting symbiosis with fungus called Tuber melanosporum which increases nutrient absorption for the plant and inhibits growth of other plants in the vicinity. It is a source of the resin ‘labdanum’ (a.k.a. ‘ladanum’) used in perfumes (similar smell to ambergris), as is Cistus ladanifer. It has no medical uses now, and such use was dwindling even in the 18th century. In the 16th century (Henry Lyte’s 1575 translation of Rembert Dodoen’s Cruydeboeck of 1554) its uses were described (directly copied from Dioscorides’ Materia Medica (70AD)) as: ‘Ladanum dronketh with olde wine, stoppeth the laske [periods], and provoketh urine. It is very good against the hardness of the matrix or mother [uterus] layde to in the manner of a pessarie, and it draweth down the secondes or afterbirth, when it is layde upon quicke coles [hot coals], and the fumigation or parfume thereof be received up into the body of women. // The same applied to the head with Myrrhe and oyle of Myrrhe, cureth the scurffe, called Alopecia, and keepeth the heare [hair] from falling of [sic], but whereas it is already fallen away, it will not cause the heare to growe agayne. // ...' and goes on in this vein about its uses for pain in the ears, and removing sores and scars and other things. Photographed in the Medicinal Garden of the Royal College of Physicians, London.

Development of brain power

Three people plucking mandrake. Gouache by Robert Bateman, 1870.

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