"X-ray analysis and protein structure"

Date:
1957
Reference:
PP/CRI/I/1/15
Catalogue details

Licence: In copyright

Credit: "X-ray analysis and protein structure". Source: Wellcome Collection.

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    X-RAY ANALYSIS AND PROTEIN STRUCTURE By F. H. C. CRICK and J. C. KENDREW The Medical Research Council Unit for the Study of the Molecular Structuri of Biological Systems, Cavendish Laboratory, Cambridge, England I. Introduction II. The Nature of X-Ray Diffraction 1. Diffraction from a Crystal. a. Crystal Lattice and Reciprocal Lattice b. Structure Determination c. Symmetry 2. Diffraction from a Fiber a. The Interpretation of Fiber Diagrams 3. Stereochemistry and Molecular Packing 4. General Remarks 5. Summary III. Fibrous Proteins and Synthetic Polypeptides 1. Synthetic Polypeptides (and Silk) a. «-Polypeptides b. /3-Polypeptides and Silk c. Polyproline d. Polyglycine 2. Fibrous Proteins a. The «-Keratin Pattern b. The 0-Keratin Pattern c. Collagen IV. Crystalline Proteins 1. The Nature of Protein Crystals 2. Direct Information a. Unit Cell and Space Group b. Molecular Weight c. Identification and Identity d. The Shape of Protein Molecules 3. The Patterson Function 4. Methods Involving Heavy Atoms a. The Heavy Atom Method b. The Method of Isomorphous Replacement c. Isomorphous Replacement and the Structure of Hemoglobin .. d. Isomorphous Replacement and the Structure of Myoglobin...