Diffuse lepromatous leprosy: Lucio phenomenon
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Diffuse lepromatous leprosy (LL): Lucio phenomenon
This is a high power view of a skin biopsy section from a case of Lucio (diffuse lepromatous) leprosy in reaction. There are acid-fast bacilli (AFB) within the vessel wall (in endothelial cells) and also in the surrounding macrophages. Wade-Fite stain.
The specific lesion of Lucio leprosy is the intravascular accumulation of AFB, which causes ischaemic damage to the skin.