Crick, J S Griffith, and L E Orgel, "Comma-less Codes". A Note for the RNA Tie Club, privately circulated, May 1956.
The file comprises three typescripts (one of which is an early draft with corrections and insertions), and a copy of the distributed mimeograph RNA Tie Club Note signed "Sydney Brenner". Forty mimeograph copies were produced.
Note: in the titles (two in holograph) to all typescripts, J S Griffith is mis-spelled "J S Griffiths", an error corrected in the distributed mimeograph.
The title-page epigraph ("It cannot be that axioms established by argumentation can suffice for the discovery of new works, since the subtlety of nature is greater many times than the subtlety of argument. Francis Bacon.") is drawn from Bacon, Aphorisms on the Interpretation of Nature and the Realm of Man, Book I of Novum organum (1620), where it appears, with its complementary second sentence, as Aphorism XXIV: "It cannot be that axioms established by argumentation should avail for the discovery of new works; since the subtlety of nature is greater many times over than the subtlety of argument. But axioms duly and orderly formed from particulars easily discover the way to new particulars, and thus render sciences active."