Dissertation in Draft: Chapter XI

Date:
1953
Reference:
PP/CRI/F/1/11
Catalogue details

Licence: In copyright

Credit: Dissertation in Draft: Chapter XI. Source: Wellcome Collection.

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    of some sort within the haemoglobin molecule* The simplest way to tackle the problem might appear to be a quantitative examination of the radial distribution curve obtainable easily be usee! here, since the recorded intensities do not extend far enough* This produces diffraction effects and also makes it im ossible to obtain an accurate estimate of the temperature factor. Thus it is difficult to use the reflections in the 4 to 5 % region without getting out of the calculation what on© put in. It is therefore necessary to concentrate on the 10 $ region, and the questi one wishes to answer is la there enough intensity in the 10 I region to be compatible with models rrade up mainly of ©¿ -helices? It is clear that one cannot «-»rely consider the peak height of .PiJUjf^, since this will partly depend on how the -helices are arranged. What one requires is a weighted sum of the 10 Ä region which one sen easily relate to a known aspect of the physical model* Fortunately it is possible to do this* 1W v \ m U. u >U íí ) teu (tX IW sh ^U, ¿'U yii KÁ yywolr W <TtV CWr ^ - 1U. fenduti. ¿5 n*V h&w>. 3 THa T'i -TTC ai :,r;rnop f « i I fi*€ *i> iir ^ k ? * r + v v kk-c whence and therefore by a well-knov n theorem,