Preparation and properties of 1:4 (or 1:5)-dimethylglyoxaline and 1:3-dimethylpyrazole / by H.A.D. Jowett and C.E. Potter.

  • Jowett, H. A. D. (Hooper Albert Dickinson)
Date:
[1903.]
Catalogue details

Licence: In copyright

Credit: Preparation and properties of 1:4 (or 1:5)-dimethylglyoxaline and 1:3-dimethylpyrazole / by H.A.D. Jowett and C.E. Potter. Source: Wellcome Collection.

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    methylglyoxaline and 1 : 3-Dimethylpyr azole By Hooper Albert Dickinson Jowett and Charles Etty Potter. During the course of the investigation by one of us on the constitution of pilocarpine (see preceding paper), it was found necessary for the purpose of comparison to prepare certain derivatives of 1-methyl- glyoxaline and 1-methylpyrazole. Accordingly, 1 : 4(or 1 : 5)-dimethyl- glyoxaline and 1 : 3-dimethylpyrazole have been prepared and charac¬ terised, and their behaviour with certain reagents studied. 1 : 4(or 1 : b)-Dimethylglyoxaline was prepared from 4(or 5)-methyl- glyoxaline, which in turn was obtained from the corresponding mer¬ captan according to the method of Gabriel and Pinkus (Ber., 1893, 26, 2203). This latter base, which had hitherto been described as a liquid, was obtained in crystals melting at 55°. The new base is a liquid forming crystalline salts. With bromine at the ordinary