Manual of the antiseptic treatment of wounds : for students and practitioners / by W. Watson Cheyne.

  • Cheyne, William Watson, Sir, 1852-1932.
Date:
1885
Catalogue details

Licence: Public Domain Mark

Credit: Manual of the antiseptic treatment of wounds : for students and practitioners / by W. Watson Cheyne. Source: Wellcome Collection.

Provider: This material has been provided by the Francis A. Countway Library of Medicine, through the Medical Heritage Library. The original may be consulted at the Francis A. Countway Library of Medicine, Harvard Medical School.

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    process is termed healing by granulation. It may be quickened if, after granulation is complete, the two sides of the wound aie brought into close contact. In this case the two layers of granulations protect each other from external irritation, they adhere, and organisation rapidly takes place while epithelium spreads over the line of union. This process is called healing by union of granulations, or healing by the third intention. There is another method of healing only seen in the case of wounds where aseptic treatment is thoroughly carried out, or in some rare instances where a crust forms ; I mean healing by organisation of blood-clot. In order to explain this I must refer to what happens to blood-clots and dead portions of tissue enclosed in the body without access of air and dust. One of the most interesting and thorough investigations on this subject has been made by Dr. H. Tillmanns of Leipzig.1 Tillmanns took portions of the liver, kidney, spleen, and lungs of rabbits, and hardened them in absolute alcohol for one to three weeks or longer. Pieces of these hardened dead tissues were then introduced with aseptic precautions into the peritoneal cavity of rabbits (in each case several pieces were used); after some days the animals were killed and the state of matters investi- gated. Twenty animals were experimented on, and into their peritoneal cavities about 100 portions of tissue were introduced. The animals did not appear the worse for the operation; the temperature remained normal, and they seemed well. Of these twenty animals only two died, both of acute peritonitis : in one case an error was committed in the treatment, the stitches were removed too early, and the intestines protruded : in the other case the animal was suffering before the operation from chronic peritonitis which afterwards became acute. When the animals were killed early, in a day or two after the operation, the masses of tissue were found to be adherent to some part of the peritoneum, and sometimes two pieces of tissue were 1 ' Experimentelle und anatomisclie Untersuchungen tiber Wunden der Leber und Niere : ein Beitrag znr Lehre von der antiseptischen Wundheilung,' Virchow's Archiv, Bd. 78, 1871).