Drug discovery from nature / S. Grabley, R. Thiericke (eds.).

Berlin : Springer, [1999], ©1999.

xix, 347 pages : illustrations ; 24 cm

The impact of natural products on drug discovery.--Recent developments in drug discovery technologies.--A central natural product pool- new approach in drug discovery strategies.--Automation strategies in drug discovery.--Synergistic use of combinatorial and natural product chemistry.--Supercritical fluid extraction (SFE)- novel strategies in the processing of biomaterials.--Secondary metabolites: from past to present.--The chemical screening approach

Myxobacteria as producers of secondary metabolites.--Trends in marine biotechnology.--Structure modification via biological derivatization methods.--Molecular biological aspects of antibiotic biosynthesis.--Combinatorial biosynthesis of antibiotics.--Impact of natural products on cell biology: low-molecular mass effectors of folding helper proteins.--Novel antibacterial drugs from microorganisms.--New antibiotics with novel mode of action

Synthetic combinatorial libraries : a new tool for antimicrobial agent discovery.--Strobilurins and oudemansins

Includes bibliographical references and index.