Ocular toxoplasmosis.

UK : University of London, 1971.

1 encoded moving image (20 min.) : sound, black and white.

00:19:45

University of London

Some restrictions

CC-BY-NC

In English

Presented by Professor E.S. Perkins, Institute of Ophthalmology, University of London. Introduced by Dr Ian Gilliland. Made by University of London Audio-Visual Centre for Postgraduate Medical Federation. Film sequences courtesy of Professor R.J.V. Pulvetaft and Westminster Hospital Medical School. Produced by Peter Bowen.

This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and 1980s, thus constituting a contemporary medical-historical archive of great interest. The lectures mostly take place in a small and intimate studio setting and are often face-to-face. The lecturers use a wide variety of resources to illustrate their points, including film clips, slides, graphs, animated diagrams, charts and tables as well as 3-dimensional models and display boards with movable pieces. Some of the lecturers are telegenic while some are clearly less comfortable about being recorded; all are experts in their field and show great enthusiasm to share both the latest research and the historical context of their specialist areas.

Segment 1 Dr Gilliland introduces Prof. Perkins, who begins the lecture by showing a film of the parasitic organism Toxoplasma gondii. He discusses how this parasite, usually found in animals, can be passed to humans. A list of the serious symptoms of congenital infection is shown. Perkins says that the infection is widespread throughout the world, and also discusses clinical diseases caused by toxoplasmosis, such as lymphadenopathy with pyrexia. He then talks about a study of pregnant women in Paris, many of whom tested positive for toxoplasmosis. Time start: 00:00:00:00 Time end: 00:05:03:23 Length: 00:05:03:23

Segment 2 Perkins continues to talk about the Paris study, in particular how many infected pregnant women went on to infect their babies. He then discusses research into whether toxoplasmosis could cause uveitis (inflammation of middle layer of eye) in the adult. The results of tests of adults with uveitis are seen in a table. Another table shows the results of treatment with an anti-toxoplasmic drug. He also talks about some anomalies in these findings. Time start: 00:05:03:23 Time end: 00:09:51:03 Length: 00:04:47:05

Segment 3 Next, Perkins discusses chorioretinitis (inflammation of the choroid and retina), including when it occurs, the symptoms and diagnosis. Photographs of lesions are seen. He then talks about this infection in relation to toxoplasmosis, and whether anti-toxoplasmosis drugs can be used to treat it. Time start: 00:09:51:03 Time end: 00:15:36:00 Length: 00:05:44:22

Segment 4 Perkins continues to talk about dosage of anti-toxoplasmosis drugs to treat chorioretinitis. He then talks about infection figures of immigrants from West Africa and the West Indies (he uses the term 'Negro population'). He discusses how the disease seems to be more severe in people with an Afro-Caribbean background. He ends the lecture by summarising his main points. Time start: 00:15:36:00 Time end: 00:19:44:24 Length: 00:04:08:24