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Duchenne muscular dystrophy carrier female

Wessex Reg. Genetics Centre

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Credit: Duchenne muscular dystrophy carrier female. Credit: Wessex Reg. Genetics Centre. Attribution 4.0 International (CC BY 4.0)

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Duchenne muscular dystrophy, chromosomes of carrier female as seen at metaphase, marked with fluorescent probe for exon 45/47. This disorder is due to a recessive gene on the X chromosome, so is usually shown only in males, who lack a second X chromosome. The probe highlights DNA associated with the defect - note that one chromosome has two bands of fluorescent yellow, while the other has only one. This is diagnostic. Biomedical Image Awards 1997.

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