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HIV and antibodies, HIV viral life cycle, illustration

  • David S. Goodsell
  • Digital Images
  • Online

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Credit: HIV and antibodies, HIV viral life cycle, illustration. David S. Goodsell, The Scripps Research Institute. Attribution 4.0 International (CC BY 4.0)

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Watercolour and ink on paper illustration of a cross section through an HIV virus particle (bottom right of image). The virus is surrounded by a membrane (light blue; circular shape) and contains viral RNA (yellow ; bottom right) encased by capsid proteins (red; conical shape). Other viral proteins (red and purple) including matrix proteins, reverse transcriptase, integrase, protease, Vif and Tat are also visible. Blood plasma surrounds the virus (yellow and brown; top and left side of image). Several broadly-neutralising antibodies found in the blood plasma (yellow; top left) are seen here binding to three HIV envelope glycoproteins (purple; extend out from the virus and look like trees rooted in the membrane). Width of image is approximately 100 nm. This image forms part of a series of illustrations which capture HIV at eight different points in the viral life cycle as it infects a cell and replicates.


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