Polarity in Drosophila oocyte - gurken mRNA
- Dr Daniel St. Johnston
Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
You can use this work for any purpose, as long as it is not primarily intended for or directed to commercial advantage or monetary compensation. You should also provide attribution to the original work, source and licence.
Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) terms and conditions https://creativecommons.org/licenses/by-nc/4.0
About this work
The localisation of gurken mRNA in the Drosophila oocyte defines the dorsal-ventral axis of the embryo. This in situ hybridisation to gurken mRNAs is in stage 10 Drosophila egg chamber. The egg chamber consists of 15 nurse cells and a large oocyte (right), which is surrounded by a layer of somatic follicle cells. Gurken is translated on the dorsal side, producing a secreted signalling molecule that induces the adjacent follicle cells to adopt a dorsal rather than a ventral fate, and this defines the polarity of the embryo's dorsal- ventral axis. Length of whole egg chamber is about 400 microns.