Human cancer cell

  • Elena Knatko/Univ. Dundee
  • Digital Images
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Attribution 4.0 International (CC BY 4.0)

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Credit

Human cancer cell. Elena Knatko/Univ. Dundee. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.

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Description

A deconvolved wide-field fluorescence microscope image of a human U20S cancer cell. The microtubules of the cytoskeleton/spindle are fluorescing green. The blue blobs are centromeres stained with human CREST autoantiserum. The red is INCENP, a protein that regulates and targets Aurora B protein kinase, which is involved in the polymerisation /depolymerisation of microtubules during mitosis.

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