On a bacillus cultivated from the blood and from the diseased tissues in syphilis / by F.S. Eve and A. Lingard.

  • Eve, Frederick Samuel, Sir, 1853-1916.
Date:
[1886]
Catalogue details

Licence: Public Domain Mark

Credit: On a bacillus cultivated from the blood and from the diseased tissues in syphilis / by F.S. Eve and A. Lingard. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    6/10 (page 6)
    was drawn out in a thread-like filament connecting the en- larged end to the rest of the bacillus. The shorter organisms were composed of two elongated or oval masses of stained protoplasm separated by a clear interval, which relatively in- creased as the bacillus became longer. The transitional forms from these to the long beaded bacilli were patent to the ob- server. If the specimens after staining were not well washed, the organisms were uniformly coloured, or the “beading” was indistinct; hence in sections this peculiar characteristic could not always be so clearly brought out; but it is well shown in Fig. 3, which was taken from a chancre in an undoubted case of syphilis. Many of the bacilli in sections of this sore were uniformly stained, or showed a clear median space such as may be seen in the shorter and more uniformly stained bacilli in Figs. 1 and 2. Other slight shades of difference may be explained by the varying conditions under which the organisms grow in culture media and in the various textures of the body. The bacilli in the case above referred to existed in great abundance, either singly or in groups, in the coimective tissue interspaces around and at the base of the sore; they were less numerous in the granulation tissue, a fact which may be explained by the observations of Ribbert on the resisting power of leucocytes to the growth of micro-organisms. This was their usual mode of distribution in chancres, but they were in many instances observed in lymph capillaries and within large clear cells. In lymphatic glands the bacilli were most abundant within and in the tissues adjoining the peripheral lymph channels, and were observed also in lymph cells. In sections of condyloma they were numerous in the connective tissue interspaces of the corium, still more so throughout the epithelium, and formed colonies on the surface. In gummata they were most numerous at the margins, where the disease was extending. In a case of phagedaenic sore, a cultivation (see Fig. 4) closely resembling that above described was obtained from the ichor flowing from its surface, and later from the lymph