Saccharine saline injections in ophthalmic practice (sodium benzoyl-sulphonic) / by L. Webster Fox.

  • Fox, Lawrance Webster, 1853-1931.
Date:
1904
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Licence: In copyright

Credit: Saccharine saline injections in ophthalmic practice (sodium benzoyl-sulphonic) / by L. Webster Fox. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    deleterious after-effect and its ready absorption. The results fol- lowing its use are undoubted, and the benefit prompt. The method by which these results are brought about is the same in all subcon- junctival injections, and I take this opportunity to refer those in- terested in the subject in the experiments of Wessely,1 undertaken to determine the physiologic action of these injections. The results of these experiments and the conclusions derived from them I be- lieve are now generally accepted. Having come to the conclusion, from practical experience, that only a few substances (the best of which are saccharine salt solution and normal salt solution) are applicable to subconjunctival ther- apy, I have extended my line of experiements to all classes of ocu- lar disease excepting glaucoma, cataract and conjunctivitis, with a view of determining the field for which this form of medication is best adapated. In consequence, I have found only a few of these diseases responded, but in these the response was prompt and un- doubted. These conditions were vitreous opacities, interstitial ker- atitis and corneal opacities. The number of injections necessary were on an average nine, one injection being made every three or four days until two injections aTe given, then once a week. An aseptic technic was employed. The conjunctiva was anesthetized by means of a few drops of a 4 per cent, solution of cocain; at the end of five minutes the solution was injected beneath the conjunctiva by means of a glass Pravaz syringe (an ordinary hypodermic syringe may be substituted), 10 to 20 c.c., with a gold needle, the lids being held apart by means of an eye speculum. The entire contents of the syringe (20 c.c.) were used in the majority of the cases, and the eye dressed with a compress saturated with an antiphlogistic lotion. The bleb sur- rounding the cornea formed by the solution seldom lasted longer than three-quarters of an hour, and the bandage was removed at the end of two or three hours. Most of the cases were walking patients. A few sensitive individuals were kept in the hospital for twenty-four hours. Absolutely no irritation or bad after- effects followed this procedure. In iritis, this method was employed in conjunction with other 1. Fox: Diseases of the Eye, Lancet, April 4, 1903, p. 187,