Cell growth and apoptosis : a practical approach / edited by George P. Studzinski.

This Practical Approach volume is unique in describing the key concepts of cell growth and cell death, particularly by apoptosis, and in providing detailed methods to study these processes. The chapters are written by experts in the field and cover a wide range of important subject areas including cell-cycle traverse, chromosomal abnormalities detected at cell division, DNA damage, and cell death or senescence. The establishment of cell lines and optimization of cell proliferation by growth factors are also described. The result is an invaluable laboratory manual for studies of growth and its abnormalities in mammalian cells. Cell Growth and Apoptosis: A Practical Approach provides state-of-the-art protocols for studies of normal and abnormal cell growth, including cancer and other cell-proliferation disorders, together with a critical appraisal of the various methodologies in use. Its coverage of human cells will make it particularly useful for health professionals.