Bacillary white diarrhœa of chicks / by Thomas Dalling and H.R. Allen.

  • Dalling, Thomas.
Date:
[1924?]
Catalogue details

Licence: In copyright

Credit: Bacillary white diarrhœa of chicks / by Thomas Dalling and H.R. Allen. Source: Wellcome Collection.

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    BACILLARY WHITE DIARRHCEA OF CHICKS. By THOMAS DALLING, M.R.C.V.S., and H. R. ALLEN, M.R.C.V.S., Wellcome Physiological Research Laboratories, Beckenham, Kent. Summary of paper read at the Eighth Annual Poultry Conference, Harper-Adams Agricultural College, Newport (Salop), on August 7, 1924. The present work on bacillary white diarrhoea at the Wellcome Physiological Research Laboratories was begun early this year. Bac¬ teriological examination of chicks received from Scotland and England resulted in the isolation of twenty-seven strains of B. pullorum from yolk sac, liver, blood, spleen and lungs. In one case B. pullorum was got from lungs only, all other organs appearing normal, an interesting fact in view of the prevalence of so-called “ brooder pneumonia/' The following experiments have been carried out in relation to the reproduction of bacillary white diarrhoea :— 1. Subcutaneous inoculation of a living culture will cause death of the chick. Two chicks each received a subcutaneous inoculation of a living culture of B. pullorum : they became obviously ill on the second day, and died on the fourth and fifth days respectively. B. pullorum was recovered from heart-blood and liver. 2. Feeding of living culture by mouth will produce bacillary white diarrhoea., (a) Three day-old chicks were fed 05 c.c. of an agar culture of B. pullorum in saline (1,000 mill, per c.c. strong) : all died between the second and fourth days. (b) Three chicks similar to above were fed with broth culture of B. pullorum instead of agar culture. All died between fourth and fifth days later. In (a) and (b) B. pullorum was recovered from the heart- blood and liver. 3. Small amounts of culture will produce bacillary white diarrhoea. Chicks. Dose of Culture. 3 0-1 c.c. 1,000 m. per c.c. emulsion 2 1/100 dose 2 1/1,000 dose 2 1/10,000 dose Results. 3 dead, second and fourth days 2 dead, sixth day. 2 dead, sixth day. 1 dead, sixth day.