[Draft Text]

Date:
[1978-1979]
Reference:
PP/CRI/H/6/14/1
Catalogue details

Licence: In copyright

Credit: [Draft Text]. Source: Wellcome Collection.

    1/87
    j> h V i ^ f ^ r _ c ¿* p ^KCfaJ » i rx'C'k. In the last two years there has been a mini-revolution in molecular genetics. When I came to California, in September 197 6, ( 7 ;pà;kptrftià*~>.eÂ*^ I had no idea that a/geneïmight be split into several pieces and I doubt if anbody else had. By the time of the annual Cold Spring Harbor Symposium, in the summer of 1977, it was clear that there was something very strange about the arrangement <¡ ^ ¿íe- 0 -fmr liuo genes I/k several eurkarytic viruses, and it seemed pieces. This has since been found to be the case. Even though the experimental evidence is still very patchy, it is now °- o- ( jyyftuK universally accepted that genef in higher organismVijfl?^ have — other base sequences interspersed within ft • This paper is not an historical account of the discovery. The earliest publication^can be tracked down by consulting Ike. COv Cold Spring Harbor Volume Chromatin. Nor does it attempt to be,a comprehensive review, both because that would take up too much space and also because experimental results are coming in all the time. I plan to presentían overall view of the present position, fluid though it is, together with some general ideas