Crystals of the amino acid histidine

  • Fernan Federici and Marcia Sartor
  • Digital Images
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Crystals of the amino acid histidine. Fernan Federici and Marcia Sartor. Attribution 4.0 International (CC BY 4.0). Source: Wellcome Collection.

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A microscopic exploration of crystals in daily life substances. Transmitted light and polarizing filters are used to provide coloration to transparent crystals in the amino acid Cysteine (Cys, C). Cysteine is a non-essential amino acid, which means that it is biosynthesized in humans. The side chain on cysteine is thiol, which is polar and thus cysteine is usually classified as a hydrophilic amino acid. The thiol side chain often participates in enzymatic reactions, serving as a nucleophile. The thiol is susceptible to oxidization to give the disulfide derivative cystine, which serves an important structural role in many proteins.

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