Incompatibilities in prescriptions : for students in pharmacy and medicine and practicing pharmacists and physicians / [Edsel Alexander Ruddiman].

  • Ruddiman, Edsel A. (Edsel Alexander), 1864-1954
Date:
1900
Catalogue details

Licence: In copyright

Credit: Incompatibilities in prescriptions : for students in pharmacy and medicine and practicing pharmacists and physicians / [Edsel Alexander Ruddiman]. Source: Wellcome Collection.

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    yellow color in a few hours and within a day it has changed to a deep red. The color varies with the iodide formed; BiOI is red; 3Bi0I,4Bi20, is yellow; Bil, is dark gray (M. & M., I. 513). II. Spirit of nitrous ether, or nitrites in acid solution, liberate iodine from iodides and give off oxides of nitrogen. 12. Nitric or nitrohydrochloric acid liberates iodine from iodides and, if sufficiently concentrated, oxidizes it to iodic acid. 13. Chlorine oxidizes iodides, forming iodine then iodic acid and in an alkaline mixture a periodate. The chlorine is changed to a chloride. 14. Chlorates in an acid solution of an iodide liberate iodine and then change it to iodic acid. Probably a similar reaction takes place in the stomach when a chlorate and an iodide are taken together. 15. lodates in acid solution with iodides liberate iodine from both. Iodides sometimes contain iodates as impurities, hence the liberation on adding an acid. 16. Arsenic compounds in acid solution with iodides liberate iodine and become ar- senous. 17. A solution of potassium iodide with arsenous acid or potassium arsenite yields a precipitate of 2KI,3Asj03 which is sparingly soluble in cold water (Watts, I. 377). When one dram of potassium iodide is added to one fluid dram of the U. S. P. solution of potassium arsenite, a white percipitate forms in a few hours ; if half that amount of iodide is added the precipitation may not take place for several days. 18. Chromates in acid solution liberate iodine and form chromic salts. 19. Permanganates in acid solutions liberate iodine and, if in great excess, oxidize it to iodic acid. 20. Hydrogen dioxide in acid solution liberates iodine from iodides, slowly in neutral mixtures. 21. The iodides some- times contain carbonates and would then have the incompati- bilities of the carbonates. 22. The alkali iodides precipitate aqueous solutions of many alkaloidal salts. In some cases this is due to the formation of compounds that are less soluble in water than the original salt. When a large excess of the alkali iodide is used it may render the alkaloidal salt less soluble in the solution than it is in water. The precipitation