Leprosy: type 1 (reversal) leprosy reaction

  • SB Lucas
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Leprosy: type 1 (reversal) leprosy reaction. SB Lucas. CC0 1.0 Universal. Source: Wellcome Collection.

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Borderline tuberculoid (BT) leprosy: type 1 (reversal) leprosy reaction This is a medium power view of a skin section from a patient with BT. Beneath the epidermis the granuloma is diffuse, rather than compact. Note also that there is oedema in the dermis (seen as 'white spaces' that contain fluid). H&E stain. This represents a mild type 1(reversal) reaction, with oedema as the main feature.

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