Proceedings of a conference to determine whether or not there is a public health question in the manufacture, distribution, or use of tetraethyl lead gasoline / Prepared by direction of the surgeon general.

  • United States. Public Health Service.
Date:
1925
Catalogue details

Licence: Public Domain Mark

Credit: Proceedings of a conference to determine whether or not there is a public health question in the manufacture, distribution, or use of tetraethyl lead gasoline / Prepared by direction of the surgeon general. Source: Wellcome Collection.

    50/128 (page 40)
    death was absorbed by the skin. In the following experiments the animals used were guinea pigs. The amount. of lead tetraethyl applied was a Seer lethal dose (1 cubic centimeter). The results follow: EXPERIMENT No. 1—Olive oil—TIwo pigs were cleansed with olive oil one minute after application of lead tetraethyl. Both pigs died. EXPERIMENT No. 2—Ordinary soap and water.—Iwo pigs were cleansed with ordinary soap and water one minute after the application of lead tetraethyl. Both pigs died. EXPERIMENT No. 3—Tincture green soap.—TIwo pigs were cleansed with tinc- ture green soap and water one minute after application oF lead gta tag: Both pigs lived. EXPERIMENT No. 4—Tincture green soap.—TIwo pigs were cleansed with tincture green soap and water two minutes after application of lead tetra- ethyl. Both pigs lived. EXPERIMENT No. 5—Tincture green soap—Two pigs were cleansed with tincture green soap and water five minutes after application of lead tetra- ethyl. Both pigs died. — EXPERIMENT No. 6—Kerosene.—TIwo pigs were cleansed with kerosene one minute after application of lead tetraethyl. Both pigs lived. EXPERIMENT No. 7—Kerosene.—Two pigs were cleansed with kerosene five minutes after application of lead tetraethyl. Both pigs lived. EXPERIMENT No. 8—Kerosene followed by tincture green soap and water. Two pigs were cleansed with kerosene, which was followed by tincture green soap and water 10 minutes after application of lead tetraethyl. Both pigs lived. HXPERIMENT No. 9—Kerosene followed by tincture green soap and water.— Two pigs were cleansed with kerosene, followed by tincture green soap and water, 15 minutes after lead tetraethyl application. Both pigs lived. EXPERIMENT No, 10—Kerosene followed by tincture green soap and water.— Two pigs were cleansed with kerosene followed by tincture green soap and water 20 minutes after application of lead tetraethyl, Both pigs lived. EXPERIMENT No, 11—Kerosene followed by tincture green soap and water— Two pigs were cleansed with kerosene followed by tincture green soap and water 25 minutes after application of lead tetraethyl. Both pigs lived. HxPERIMENT No. 12—Kerosene followed by tincture green soap and water.— Two pigs were cleansed with kerosene followed by tincture green soap and water 30 minutes after application of lead tetraethyl. One pig lived. One pig died. | | EXPERIMENT No. 13—Kerosene followed by tincture green soap and water.— Four pigs were cleansed with kerosene followed by tincture green soap and water. Two pigs were cleansed 35 minutes after exposure. Two pigs were cleansed 40 minutes after exposure. All four pigs died. Conclusion: Both olive oil and common soap and water proved valueless as agents to remove the lead tetraethyl from the skin. Tincture green soap was effective if used within two minutes after the application of the lead compound. Kerosene proved to be the best agent tried; all pigs lived that were kerosene treated up to 30 minutes. It was observed that the skin of the pigs that were treated with kerosene alone became tense, interfering with the movements of the animals. The skin would also crack and _ tear, causing great discomfort. It was found that following the application of the kerosene by. tincture green soap and water removed the kerosene, leaving the skin soft and pliable.