The influence of changes in the intraocular circulation on the intraocular pressure / by E.E. Henderson and E.H. Starling.

  • Henderson, Edward Erskine, 1870-1929.
Date:
1904
Catalogue details

Licence: In copyright

Credit: The influence of changes in the intraocular circulation on the intraocular pressure / by E.E. Henderson and E.H. Starling. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    observation, but all agree in the main principle that the intraocular tension, in the absence of special local vaso-motor influences, follows the general blood-pressure, and the same result was obtained by Parsons. The effect of mechanical interference with the circulation can be best judged of by giving a record of a typical experiment on a dog. At the commencement of the experiment a rubber capsule on a metal tube was passed through the left femoral artery so as to lie in the thoracic aorta. The left vertebral and subclavian arteries were tied. Adjustable liga- tures were put loosely round the right vertebral and subclavian arteries. The blood-pressure was measured by a cannula in the left carotid artery, and the intraocular pressure was taken in the right eye. At the beginning of the observations the blood-pressure stood at 128 mm. Hg. and the intraocular pressure at 26 mm. Hg. The aortic obturator was then distended. The blood-pressure immediately rose to 158 mm. Hg. and the intraocular pressure to 34, both remaining practically constant at this height for 100 seconds (see Fig. 2, A). The aorta being still Fig. 2, A. To illustrate the effects of mechanical interference with the circulation in a dog. Blood-pressure measured in left carotid, intraocular pressure in right eye. From P to S the aorta was occluded. From Q to R the right vertebral and subclavian were also occluded. In this, as in all the tracings, the scale to the right indicates the intraocular pressure reduced to millimetres of mercury. Time marker 10 seconds intervals. obstructed, the ligatures round the right vertebral and subclavian arteries were drawn tight. The blood-pressure now rose to 180 mm., and the intraocular pressure rose to 40. After another 50 seconds this