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Blister pack of chloroquine antimalarial tablets. Chloroquine is used to prevent and treat the infectious disease malaria. Malaria is caused by parasites (Plasmodium species) which enter the blood when inefcted mosquitoes feed. Side effects of chloroquine include vomitting, nausea and headache. Retinopathy (damage to the retina) is a rare eye condition associated with long term use over many years. Drug resistance against antimalarials is increasing.