244 results filtered with: Pink
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Catharanthus roseus (L.)G.Don Apocynaceae. Madagascar Periwinkle Distribution: Madagascar. It is the source of vincristine and vinblastine, which impair cell multiplication by interfering with microtubule assembly, causing metaphase arrest and are effective medications for leukaemias, lymphomas and some solid tumours. The mortality from childhood leukaemia fell from 100% to 30% once it was introduced - not a drug that could ethically be tested by double-blind trials. These chemicals were initially discovered by investigators in 1958 who were looking for cures for diabetes so tested this plant which was being used in the West Indies to reduce blood sugar levels. There are 70 different alkaloids present in this plant, and some - catharanthine, leurosine sulphate, lochnerine, tetrahydroalstonine, vindoline and vindolinine - lower blood sugar levels. However, the toxicity of this plant is such that this is not a plant to try at home for diabetic management. The vincristine content of the plant is 0.0003%, so two kilograms of leaf are required to produce sufficient vincristine for a single course of treatment for a child (6gm). Fortunately it is a vigorous weed and easy to grow in the tropics. Artificial synthesis has now been achieved. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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Damaged human hair, bleached and straightened, SEM
Anne Weston, Francis Crick Institute
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Adipose Tissue
Odra Noel
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Thermogram of an infected middle finger, left hand.
Thermal Vision Research
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Drosophila leg, tarsus, SEM
Anne Weston, Francis Crick Institute
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Bioblasts
Odra Noel
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Bacterial microbiome mapping, bioartistic experiment
François-Joseph Lapointe, Université de Montréal
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Diatom frustule, SEM
Anne Weston, Francis Crick Institute
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Prostate cancer cell spheroid, SEM
Izzat Suffian, David McCarthy & Khuloud T. Al-Jamal
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Future element
Odra Noel
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HeLa cells, immortal human epithelial cancer cell line, SEM
Anne Weston, Francis Crick Institute
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Dermatofibroma, LM
Kevin Mackenzie, University of Aberdeen
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Human heart (mitral valve) tissue displaying calcification
Sergio Bertazzo, Department of Materials, Imperial College London
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GABAergic and Glutamatergic neurons in the zebrafish brain
Kate Turner, Dr Steve Wilson
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Conjoined twin piglets
Michael Frank, Royal Veterinary College
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Guava, axial view, MRI
Alexandr Khrapichev, University of Oxford
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Lung cancer cells grown in culture, SEM
Anne Weston, Francis Crick Institute
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Echinacea purpurea (L.) Moench Asteraceae. Coneflower. Distribution: North America. Austin (2004) records that the roots were chewed, or used as a tincture for coughs by the Choctaw. It was combined with Rhus typhina to treat venereal disease by the Delaware. Very little record of this being used by Native Americans, who used E. angustifolia very widely - Regarded as a panacea and magical herb. This and E. pallida were used to treat snakebite, spider bite, cancer, toothache, burns, sores, wounds, flu and colds. E. purpurea in modern times has been used as an ‘immunostimulant’, but is known to cause a fall in white cell count, and to be purely a placebo. Licensed for use as a Traditional Herbal Medicine, which does not require proof of efficacy, in the UK. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley
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HeLa cells, immortal human epithelial cancer cell line, SEM
Anne Weston, Francis Crick Institute
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Breast cancer cell spheroid treated with doxorubicin, SEM
Khuloud T. Al-Jamal, David McCarthy & Izzat Suffian
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HeLa cells, immortal human epithelial cancer cell line, SEM
Anne Weston, Francis Crick Institute
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HeLa cells, LM
Kevin Mackenzie, University of Aberdeen
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Dopaminergic neurons in the zebrafish forebrain. Confocal micrograph of a 4 day old transgenic zebrafish embryo viewed from a lateral aspect. Neurons in the olfactory bulb, telencepahlon, ventral diencephalon, pretectum and hypothalamus are labelled in green. Axonal tracts are shown in cyan and neuropil in magenta. In order to show the anatomy of the brain better the skin and eyes of the embryo have been removed post-fixation.
Kate Turner, Dr Steve Wilson
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Paeonia officinalis 'Flore Pleno'
Dr Henry Oakeley
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HeLa cell, immortal human epithelial cancer cell line, SEM
Anne Weston, Francis Crick Institute