147 results
- Videos
- Online
Research on anthelmintics.
Date: 1962- Videos
Drug trials - the dark side.
Date: 2006- Archives and manuscripts
"Compounds sent for testing" by TRC member companies
Date: 1944-1948Reference: WF/TRC/02/110Part of: Wellcome Foundation Ltd- Pictures
Magnified detail of the yellow toxin staphylococcus aureas and its reaction of resistance to penicillin, on a blood agar plate. Watercolour by Barbara E. Nicholson, 1947.
Nicholson, BarbaraDate: 1947Reference: 31985iPart of: Barbara Nicholson medical illustration collection.- Books
AIDS and substance abuse / Larry Siegel, editor.
Date: [1988]- Archives and manuscripts
Wellcome Press Cuttings
Date: April - June 1986Reference: WF/M/PC/05/04/02Part of: Wellcome Foundation Ltd- Archives and manuscripts
Wellcome Press Cuttings
Date: July - October 1986Reference: WF/M/PC/05/04/03Part of: Wellcome Foundation Ltd- Archives and manuscripts
Wellcome Press Cuttings
Date: May - July 1987Reference: WF/M/PC/05/05/03Part of: Wellcome Foundation Ltd- Videos
- Online
Allergic bronchial reactions. Asthma.
Date: 1973- Archives and manuscripts
Sawyer - Schlichtergroll
Date: 1949-1985Reference: PP/MLV/C/19/8Part of: Vogt, Dr Marthe Louise (1903-2003)- Archives and manuscripts
Iggo - Institute for Scientific Information
Date: 1942-1986Reference: PP/MLV/C/9/1Part of: Vogt, Dr Marthe Louise (1903-2003)- Videos
Pfizer Sandwich.
Date: 1963- Archives and manuscripts
Patzig - Phillis
Date: 1950-1988Reference: PP/MLV/C/16/5Part of: Vogt, Dr Marthe Louise (1903-2003)- Archives and manuscripts
Wellcome Press Cuttings
Date: December 1985 - March 1986Reference: WF/M/PC/05/04/01Part of: Wellcome Foundation Ltd- Digital Images
- Online
Papaver somniferum L. Papaveraceae Opium Poppy Distribution: Asia minor, but has been dated to 5000BC in Spanish caves. Now grows almost everywhere. The oldest medicine in continuous use, described in the Ebers' papyrus (1550 BC), called Meconium, Laudanum, Paregoric and syrup of poppies. Culpeper (1650) on Meconium '...the juyce of English Poppies boyled till it be thick' and 'I am of the opinion that Opium is nothing else but the juyce of poppies growing in hotter countries, for such Opium as Authors talk of comes from Utopia.[he means an imaginary land, I suspect]’]. He cautions 'Syrups of Poppies provoke sleep, but in that I desire they may be used with a great deal of caution and wariness...' and warns in particular about giving syrup of poppies to children to get them to sleep. The alkaloids in the sap include: Morphine 12% - affects ?-opioid receptors in the brain and causes happiness, sleepiness, pain relief, suppresses cough and causes constipation. Codeine 3% – mild opiate actions – converted to morphine in the body. Papaverine, relaxes smooth muscle spasm in arteries of heart and brain, and also for intestinal spasm, migraine and erectile dysfunction. Not analgesic. Thebaine mildly analgesic, stimulatory, is made into oxycodone and oxymorphone which are analgesics, and naloxone for treatment of opiate overdose – ?-opioid receptor competitive antagonist – it displaces morphine from ?-opioid receptors, and constipation caused by opiates. Protopine – analgesic, antihistamine so relieves pain of inflammation. Noscapine – anti-tussive (anti-cough). In 2006 the world production of opium was 6,610 metric tons, in 1906 it was over 30,000 tons when 25% of Chinese males were regular users. The Opium wars of the end of the 19th century were caused by Britain selling huge quantities of Opium to China to restore the balance of payments deficit. Laudanum: 10mg of morphine (as opium) per ml. Paregoric: camphorated opium tincture. 0.4mg morphine per ml. Gee’s Linctus: up to 60 mg in a bottle. J Collis Browne’s chlorodyne: cannabis, morphine, alcohol etc. Kaolin and Morph. - up to 60 mg in a bottle. Dover’s Powders – contained Ipecacuana and morphine. Heroin is made from morphine, but converted back into morphine in the body (Oakeley, 2012). One gram of poppy seeds contains 0.250mgm of morphine, and while one poppy seed bagel will make a urine test positive for morphine for a week, one would need 30-40 bagels to have any discernible effect. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley- Digital Images
- Online
Papaver somniferum L. Papaveraceae Opium Poppy Distribution: Asia minor, but has been dated to 5000BC in Spanish caves. Now grows almost everywhere. The oldest medicine in continuous use, described in the Ebers' papyrus (1550 BC), called Meconium, Laudanum, Paregoric and syrup of poppies. Culpeper (1650) on Meconium '...the juyce of English Poppies boyled till it be thick' and 'I am of the opinion that Opium is nothing else but the juyce of poppies growing in hotter countries, for such Opium as Authors talk of comes from Utopia [he means an imaginary land, I suspect]’. He cautions 'Syrups of Poppies provoke sleep, but in that I desire they may be used with a great deal of caution and wariness...' and warns in particular about giving syrup of poppies to children to get them to sleep. The alkaloids in the sap include: Morphine 12% - affects ?-opioid receptors in the brain and causes happiness, sleepiness, pain relief, suppresses cough and causes constipation. Codeine 3% – mild opiate actions – converted to morphine in the body. Papaverine, relaxes smooth muscle spasm in arteries of heart and brain, and also for intestinal spasm, migraine and erectile dysfunction. Not analgesic. Thebaine mildly analgesic, stimulatory, is made into oxycodone and oxymorphone which are analgesics, and naloxone for treatment of opiate overdose – ?-opioid receptor competitive antagonist – it displaces morphine from ?-opioid receptors, and reverses the constipation caused by opiates. Protopine – analgesic, antihistamine so relieves pain of inflammation. Noscapine – anti-tussive (anti-cough). In 2006 the world production of opium was 6,610 metric tons, in 1906 it was over 30,000 tons when 25% of Chinese males were regular users. The Opium wars of the end of the 19th century were caused by Britain selling huge quantities of Opium to China to restore the balance of payments deficit. Laudanum: 10mg of morphine (as opium) per ml. Paregoric: camphorated opium tincture. 0.4mg morphine per ml. Gee’s Linctus: up to 60 mg in a bottle. J Collis Browne’s chlorodyne: cannabis, morphine, alcohol etc. Kaolin and Morph. - up to 60 mg in a bottle. Dover’s Powders – contained Ipecacuana and morphine. Heroin is made from morphine, but converted back into morphine in the body (Oakeley, 2012). One gram of poppy seeds contains 0.250mgm of morphine, and while one poppy seed bagel will make a urine test positive for morphine for a week, one would need 30-40 bagels to have any discernible effect. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
Dr Henry Oakeley- Archives and manuscripts
Burroughs Wellcome & Co, Private Letter Book 17
Date: February - June 1904Reference: WF/E/03/17 (copy, part 2)Part of: Wellcome Foundation Ltd- Archives and manuscripts
- Online
Burroughs Wellcome & Co, Private Letter Book 17
Date: February - June 1904Reference: WF/E/03/17Part of: Wellcome Foundation Ltd- Archives and manuscripts
Burroughs Wellcome & Co, Private Letter Book 17
Date: February - June 1904Reference: WF/E/03/17 (copy, part 1)Part of: Wellcome Foundation Ltd- Archives and manuscripts
Burroughs Wellcome & Co, Private Letter Book 11
Date: October 1902 - January 1903Reference: WF/E/03/11 (Copy, part 2)Part of: Wellcome Foundation Ltd- Archives and manuscripts
- Online
Burroughs Wellcome & Co, Private Letter Book 11
Date: October 1902 - January 1903Reference: WF/E/03/11Part of: Wellcome Foundation Ltd- Archives and manuscripts
Burroughs Wellcome & Co, Private Letter Book 11
Date: October 1902 - January 1903Reference: WF/E/03/11 (Copy, part 1)Part of: Wellcome Foundation Ltd- Archives and manuscripts
Burroughs Wellcome & Co, Private Letter Book 6
Date: January 1901 - July 1901Reference: WF/E/03/06 (copy, part 2)Part of: Wellcome Foundation Ltd- Archives and manuscripts
Burroughs Wellcome & Co, Private Letter Book 6
Date: January 1901 - July 1901Reference: WF/E/03/06 (copy, part 1)Part of: Wellcome Foundation Ltd- Archives and manuscripts
- Online
Burroughs Wellcome & Co, Private Letter Book 6
Date: January 1901 - July 1901Reference: WF/E/03/06Part of: Wellcome Foundation Ltd