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  • Oenothera macrocarpa Nutt. Onagraceae. Ozark Sundrops, Bigfruit Evening Primrose. Formerly O. missouriensis. Distribution: South central USA. O. macrocarpa does not appear to have been used medicinally, but other species are so used. Austin (2004) records that O. biennis (Evening Primrose) was used by Native Americans as a potherb in West Virginia. Leaves as salad, roots boiled like potato also infusion to treat obesity and relieve piles (Cherokee)