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31 results
  • Leukaemia: Nothnagel, 1901
  • Leukaemia: Nothnagel, 1901
  • Leukaemia karyotype, acute myelodysplasia
  • Leukaemia karyotype t(4;11) etc
  • Myelodysplasia (leukaemia) karyotype
  • Acute promyelocytic leukaemia karyotype
  • Hyperdiploid acute lymphoblastic leukaemia
  • Acute myelomonocytic leukaemia +eosinophilia
  • Acute myeloblastic leukaemia karyotype
  • Blood smear showing acute lymphatic leukaemia.
  • Chronic myeloid leukaemia karyotype 9;22
  • Blood from a case of leukaemia
  • Blood cells in myeloid leukaemia stained with Ehrlich's triple stain, as seen under a microscope. Watercolour after A. Goodall, 1912.
  • Leukamia karyotype t(8;14)
  • Catharanthus roseus (L.)G.Don Apocynaceae. Madagascar Periwinkle Distribution: Madagascar. It is the source of vincristine and vinblastine, which impair cell multiplication by interfering with microtubule assembly, causing metaphase arrest and are effective medications for leukaemias, lymphomas and some solid tumours. The mortality from childhood leukaemia fell from 100% to 30% once it was introduced - not a drug that could ethically be tested by double-blind trials. These chemicals were initially discovered by investigators in 1958 who were looking for cures for diabetes so tested this plant which was being used in the West Indies to reduce blood sugar levels. There are 70 different alkaloids present in this plant, and some - catharanthine, leurosine sulphate, lochnerine, tetrahydroalstonine, vindoline and vindolinine - lower blood sugar levels. However, the toxicity of this plant is such that this is not a plant to try at home for diabetic management. The vincristine content of the plant is 0.0003%, so two kilograms of leaf are required to produce sufficient vincristine for a single course of treatment for a child (6gm). Fortunately it is a vigorous weed and easy to grow in the tropics. Artificial synthesis has now been achieved. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • TEM of a lymphoblast.
  • Catharanthus roseus (Madagascar periwinkle)
  • TEM Jurkat T cell showing typical clumped heterochromatin.
  • Follicular non-Hodgkinson's lymphoma
  • TEM Jurkat T cell early apoptopsis
  • Antianemil ... : Testimedul / LADA, Laboratorios Aliados de América, S.A.
  • Antianemil ... : Testimedul / LADA, Laboratorios Aliados de América, S.A.
  • Animal research has benefits for us all- and for animals too / Understanding Animal Research.
  • Animal research has benefits for us all- and for animals too / Understanding Animal Research.
  • El linfatismo se manifiesta en mil formas distintas ... Ganglios Linfaticos Combinados LADA son la terapeutica especifica moderna para todos ellas : Los sulfas... son un descubrimiento maravilloso pero... tambien un toxico temible : Lipoide Hepatico Lada le permetira usarlos a grandes dosis sin consecuencias / LADA, Laboratorios Aliados de América, S.A.
  • El linfatismo se manifiesta en mil formas distintas ... Ganglios Linfaticos Combinados LADA son la terapeutica especifica moderna para todos ellas : Los sulfas... son un descubrimiento maravilloso pero... tambien un toxico temible : Lipoide Hepatico Lada le permetira usarlos a grandes dosis sin consecuencias / LADA, Laboratorios Aliados de América, S.A.
  • El linfatismo se manifiesta en mil formas distintas ... Ganglios Linfaticos Combinados LADA son la terapeutica especifica moderna para todos ellas : Los sulfas... son un descubrimiento maravilloso pero... tambien un toxico temible : Lipoide Hepatico Lada le permetira usarlos a grandes dosis sin consecuencias / LADA, Laboratorios Aliados de América, S.A.
  • El linfatismo se manifiesta en mil formas distintas ... Ganglios Linfaticos Combinados LADA son la terapeutica especifica moderna para todos ellas : Los sulfas... son un descubrimiento maravilloso pero... tambien un toxico temible : Lipoide Hepatico Lada le permetira usarlos a grandes dosis sin consecuencias / LADA, Laboratorios Aliados de América, S.A.
  • Catharanthus roseus (Madagascar periwinkle)
  • Down syndrome human karyotype 47,XY,+21